Required for selection of future bud sites. Cooperates with other bud site selection proteins to recognize a spatial landmark during mitosis and they subsequently become a landmark for downstream polarity establishment factors that coordinate budding and cytokinesis. Involved in the septin organization at the bud neck (By similarity).

Belongs to the BUD4 family.

1378 amino acids

MIPNDAEGAMDSLLKEIDHEMEVTIGTIDAQEDHSKQKEETEATNQQTWKLPLQDIGDETMDMLVKHNTKNNVINPNFNKKDVDTNESPKNNNDKNVVFNDNVQLLELSANMDESVLMSTPTKSDIDISPNKVLINLGDDIANESNEDNKLPLDNKTESEDSDLVSTMLLSKIPITHTENINDFYEKKSTDIRASTSRISSVSSDIEGTPLPTTVQTDQFELLKQAMKQTFEEDNNSNIDISPLKESLLSSELKTKQNLSIEQNEETSVDSIDNSVIHNSEYEVHARSNEREEENENDFENSIEDLEISTHVIEKSPSIEAISTLDPNTDNNKEHFIINNITKDSTFIEVTSDSKIQIDLKDSPENTLHTNEDQKEANTENVASETNIKETDQVIHIPTLTEEEISTITNITNDTETTEEGSKAEEDAKNSDVSNSQNSESINTTITNSLIGIDQNLTNKSSDITNDYEEPPKENELKSSPDVIEKGHSSIEHFDDEKITNSSALGTSNYISIPLDTLQEATPVTDSGKTFELQNQDSDNINSERIQNLNGSTPVEEKFNADDELLKTNQSHITQNKDKSNINEIDNSGTTSIVSDHVVAPILPPLPKIDKIFIDDPFGEEYDISNDSIDLTKSTRPGDYLSIWHIQEEELKQVSPASTTNSQFSNRILSNASSNASAESRISSTAFKFKPRIVSRSRYINPESRVNSFNISEEMILPQLYGALDPMRRSSRMSRTIQNSIKANRQKSEQYAGTRKYSIEIQPNQESRISSRIISNKLEEVSSENDKVETMNNSITMDGSFQLLPSFLDNSFGEQLDLTFSKFAKDVLSLRSSSLAQSEIHDNSINIWGEDNFIGNTSKNNDHNAMLDSKNKLLEVTDDEKSISESINKDIFADGILKSSIFNDITVSRGLNINGLDVDLSDSESVRVSLLTAETDASESGTPIKNTVKDSHVSSPFKVVNISKWKNQDGPESDHEVEEIAEIQIEAEKSSESIADISPIKMKPFVDTVVIEEPSQTALVDAGSLYLKLKGCLNIKLTGIKHHDARYCFEFDNGRNSIQTAWAVIPSDGDIRVNHDFESTVFEVGSKLYVTLKCKYTPPKTEIVEVVEKVLIPKKKLFGKAEYKYEKRFVQRDSKKDEWNNLFARDGSFGRAEVLLDHTFLNSVKYNKRNCTFDMMNEWTRLNDKENIENVFNIPRKPKYKVADLKMEVCYLDRVSNKEVFPVSFDKCEMIIKKYKEQLLISKEGYLMQEGGDVCNNLVRRFFKLQGTDLIGYHEVSNLPVVTINMLKVIDVVSSDDLKEEEGKQRSGNSKRNFTDHVLFGGCIQLVFTDEEVINLYADTSAQEKIEWYSKLKKTVDLNICHQPWVTKLAEAQKLEEC

155.3 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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