Protein
Probable inner membrane protein BTH_II0599
Organism
Burkholderia thailandensis (strain ATCC 700388 / DSM 13276 / CIP 106301 / E264)
Function
(Microbial infection) Probably transports the toxic C-terminal region of CdiA-2 from B.pseudomallei strain 1026b across the inner membrane to the cytoplasm, where CdiA has a toxic effect. Expression in E.coli makes the bacteria sensitive to the tRNase domain of B.pseudomallei strain 1026b CdiA-2.
Sequence
MQLIEVSAKTGYVWFRQGIWLFRRNPLAFVTLFFTYLLAMMLVSLVPVIGAALPLLLIPGIAVGFMAACRDTIAGKQVLPTILIDGFRSYGPIVTQRLLTLGGLYIVSMAAVFACSALGDGGTLLKIMFGLGAENLGPDALESPGFKIAALIAAALYAPVAMMFWFAPVLTAWHDVPPVKALFFSVVSCWRNKGAFTVYGLLWFALALGVSFGLAALMQALGASAYALMVMMPASIVITAMLYCSFYATYRGCFGVQEPGAPKLPNTSDR