Protein
2-epi-valiolone synthase
Organism
Actinosynnema mirum (strain ATCC 29888 / DSM 43827 / NBRC 14064 / IMRU 3971)
Function
Catalyzes the conversion of sedoheptulose 7-phosphate to 2-epi-valiolone, which may serve as an alternative precursor for aminocyclitol biosynthesis.
Similarity
Belongs to the sugar phosphate cyclases superfamily. EVS family.
Sequence
MDSPAGYRIHDNIPLPGNLDQVDVHVTRDDDYRIHVLPDVDRAVDALLTELDGRRAVVITDDVVADLHEGRVSAELAARGQLIGRTAIRAGEKSKSLTTAFELIDWLAEVNLARRDVVIALGGGVVVDTVGFVASAYMRGVPYVNMPTTLLAQVDAGIGGKVAVDHSEAKNLVGAFYQPKAVISCLEHLRTLDTRQIRSGLAEVVKKAVIASPELFDYIEANADDLLACASPAIDVLVHAAGAIKTKLVGRDPYEIDLRRPLNFGHTTGHAVETVTNYGPVLHGEAVAFGMVVAVDVARARGLVVPEVADRVTALIRRLGLPVALEELGAVPRVDDVVAALLKIRQIRDGSLRFVLPVELGATVIAEDVTEEEVRAALVRLR