About Products Protein Database Contact

Acel_0264

Gene
Acel_0264
Protein
Aminodeoxyfutalosine deaminase
Organism
Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
Length
356 amino acids
Function
Catalyzes the deamination of aminodeoxyfutalosine (AFL) into futalosine (FL), a step in the biosynthesis of menaquinone (MK, vitamin K2). Is very poorly efficient on 1-(6-amino-9H-purin-9-yl)-1-deoxy-N-ethyl-beta-D-ribofuranuronamide (NECA), adenosine, 5'-methylthioadenosine, 5'-deoxyadenosine, 2'-deoxyadenosine, and AMP as substrate.
Similarity
Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.
Mass
38.176 kDa
Sequence
MTPHDPVSVEAVPKIELHVHLEGTVEPATVLDIAARNGLALPVSTVDELSALYRVTTFSDFLRLWILTTNVLRKAEDFSQVVVDYARRAKRHGAVYIEGIFSPVERVMRGVGWAEIFDGYCEGAERAYAEHGVVVRLTPEAYRGADPELVAEMVRYAGRYRDRGVVGVGIGGDERARPTRHYAAAFAPAVDLGLGVVPHAGEFPLFPDGASGAATLRETIEALNPVRIRHGIAAAADPALVAVIRERGIVLDVCPTSNLRTGAIRDLADHPLPRLAAAGIPCTVGTDDPAVFDTDLSREFTIAARLGVEPRLLYDAGITGALCDDDVKSHLRQIGAATTWPTTTATWSTTAAGESL