ATG9

Autophagy-related protein 9

997 amino acids

Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Required for mitophagy. Cycles between the PAS and the cytoplasmic vesicle pool and may participate in supplying membrane for the growing autophagosome. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. Different machineries are required for anterograde trafficking to the PAS during either the Cvt pathway or bulk autophagy and for retrograde trafficking. Anterograde trafficking requires an intact actin cytoskeleton and proper retrograde trafficking of from the PAS to the cytoplasmic vesicles requires the ATG1-ATG13 complex and the phosphatidylinositol 3-kinase complex I. Recruits ATG23 and ATG8 to the PAS.

Belongs to the ATG9 family.

115.452 kDa

MERDEYQLPNSHGKNTFLSRIFGLQSDEVNPSLNSQEMSNFPLPDIERGSSLLHSTNDSREDVDENDLRVPESDQGTSTEEEDEVDEEQVQAYAPQISDGLNGDHQLNSVTSKENVLETEKSNLERLVEGSTDDSVPKVGQLSSEEEEDNEFINNDGFDDDTPLFQKSKIHEFSSKKSNTIEDGKRPLFFRHIYQNNRPQRDTQKLFTSSNAIHHDKDKSANNGPRNINGNQKHGTKYFGSATQPRFTGSPLNNTNRFTKLFPLRKPNLLSNISVLNNTPEDRINTLSVKERALWKWANVENLDIFLQDVYNYYLGNGFYCIILEKILNICTLLFVVFVSTYMGHCVDYSKLPTSHRVSDIIIDKCYSNSITGFTKFFLWMFYFFVILKIVQLYFDVQKLSELQNFYKYLLNISDDELQTLPWQNVIQQLMYLKDQNAMTANVVEVKAKNRIDAHDVANRIMRRENYLIALYNSDILNLSLPIPLFRTNVLTKTLEWNINLCVMGFVFNESGFIKQSILKPSQREFTREELQKRFMLAGFLNIILAPFLVTYFVLLYFFRYFNEYKTSPGSIGARQYTPIAEWKFREYNELYHIFKKRISLSTTLANKYVDQFPKEKTNLFLKFVSFICGSFVAILAFLTVFDPENFLNFEITSDRSVIFYITILGAIWSVSRNTITQEYHVFDPEETLKELYEYTHYLPKEWEGRYHKEEIKLEFCKLYNLRIVILLRELTSLMITPFVLWFSLPSSAGRIVDFFRENSEYVDGLGYVCKYAMFNMKNIDGEDTHSMDEDSLTKKIAVNGSHTLNSKRRSKFTAEDHSDKDLANNKMLQSYVYFMDDYSNSENLTGKYQLPAKKGYPNNEGDSFLNNKYSWRKQFQPGQKPELFRIGKHALGPGHNISPAIYSTRNPGKNWDNNNNGDDIKNGTNNATAKNDDNNGNNDHEYVLTESFLDSGAFPNHDVIDHNKMLNSNYNGNGILNKGGVLGLVKEYYKKSDVGR

ATG9

Autophagy-related protein 9

997 amino acids

Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation (PubMed:8224160, PubMed:7593182, PubMed:8663607, PubMed:10735854, PubMed:14504273). Plays a key role in the organization of the preautophagosomal structure/phagophore (PAS) assembly site, the nucleating site for formation of the sequestering vesicle (PubMed:10662773, PubMed:11689437, PubMed:17329962, PubMed:17426440, PubMed:24905091). Required for mitophagy (PubMed:18818209). Cycles between the PAS and the cytoplasmic vesicle pool and may participate in supplying membrane for the growing autophagosome (PubMed:18829864, PubMed:22826123). Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress (PubMed:17132049). Recruits vesicle-tethering proteins TRS85 and YPT1 to the autophagosome formation site (PubMed:23129774). Recruits also ATG23 and ATG8 to the PAS (PubMed:14504273).

Belongs to the ATG9 family.

115.403 kDa

MERDEYQLPNSHGKNTFLSRIFGLQSDEVNPSLNSQEMSNFPLPDIERGSSLLHSTNDSREDVDENDLRVPESDQGTSTEEEDEVDEEQVQAYAPQISDGLDGDHQLNSVTSKENVLETEKSNLERLVEGSTDDSVPKVGQLSSEEEEDNEFINNDGFDDDTPLFQKSKIHEFSSKKSNTIEDGKRPLFFRHILQNNRPQRDTQKLFTSSNAIHHDKDKSANNGPRNINGNQKHGTKYFGSATQPRFTGSPLNNTNRFTKLFPLRKPNLLSNISVLNNTPEDRINTLSVKERALWKWANVENLDIFLQDVYNYYLGNGFYCIILEKILNICTLLFVVFVSTYMGHCVDYSKLPTSHRVSDIIIDKCYSNSITGFTKFFLWMFYFFVILKIVQLYFDVQKLSELQNFYKYLLNISDDELQTLPWQNVIQQLMYLKDQNAMTANVVEVKAKNRIDAHDVANRIMRRENYLIALYNSDILNLSLPIPLFRTNVLTKTLEWNINLCVMGFVFNESGFIKQSILKPSQREFTREELQKRFMLAGFLNIILAPFLVTYFVLLYFFRYFNEYKTSPGSIGARQYTPIAEWKFREYNELYHIFKKRISLSTTLANKYVDQFPKEKTNLFLKFVSFICGSFVAILAFLTVFDPENFLNFEITSDRSVIFYITILGAIWSVSRNTITQEYHVFDPEETLKELYEYTHYLPKEWEGRYHKEEIKLEFCKLYNLRIVILLRELTSLMITPFVLWFSLPSSAGRIVDFFRENSEYVDGLGYVCKYAMFNMKNIDGEDTHSMDEDSLTKKIAVNGSHTLNSKRRSKFTAEDHSDKDLANNKMLQSYVYFMDDYSNSENLTGKYQLPAKKGYPNNEGDSFLNNKYSWRKQFQPGQKPELFRIGKHALGPGHNISPAIYSTRNPGKNWDNNNNGDDIKNGTNNATAKNDDNNGNNDHEYVLTESFLDSGAFPNHDVIDHNKMLNSNYNGNGILNKGGVLGLVKEYYKKSDVGR

ATG9

Autophagy-related protein 9

961 amino acids

Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Required for mitophagy. Cycles between the PAS and the cytoplasmic vesicle pool and may participate in supplying membrane for the growing autophagosome. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. Different machineries are required for anterograde trafficking to the PAS during either the Cvt pathway or bulk autophagy and for retrograde trafficking.

Belongs to the ATG9 family.

110.107 kDa

MGDSESVNQDHGRNTFLSRVFGLQPDDITTSIRTGDMSRYPLNAYSGGSEMFSGSPTSSRIDDDDDDDEGRVPESDQQSSSGDNSDDIKANDDVIEDVELTDGNGDNYTNSKMINTNYSIFGSLRKVGQQSSDEEDDGSLSNEEEDIDEEDEIDEIDADEPLFVNSTSQRKQKRKSSVNFKNGSEMSSLLFQRILNKKDSKSNGEASNKMFTSSNQGNHNYKYRNGHDLEGGVHFNKKEGRRNSLFGSHEAGGHKSHNSAPSKGPNLLKNISILNNTPSNKVYTLSPKERALWKWANVENLDVFLQEVYKYYLGSGFSCIVLRKLLNLTTLIFVVYISTYLGYCIDYSKLPTSSRLSDIIIDQCYTTRITGITKGLLWVFYVFVGLKVVQFYFDLQNLTDMHNFYNYLLGISDNELQTIPWQNIIQQLMYLKDQNALTANVVEVKAKNKIDPLVVANRIMRKDNYLIALYNENILDLSLPIPFYKESILTKTLEWNINLCIIGFAFNESGFIKQSFLKKSQHQFITEELRKRFMLAGFLNIILSPFLVTYFVLLYFLRYFNEFKTSPGTIGARQYTPMAEWTFREFNELYHIFQKRLGLSTVIADKYINQFPKESTDLILKFISFISGSFVAVLMSLTLLDSENFLNFEVTKDRSVLFYITVFGAIWSVCRNSISDEYKVYDPDETIKELSEFTHYLPKEWEGKHHTEDVKQEFCKLYNIRLIILLRELASLVLTPFILWFSLPACSDRIVDFFSDSSTYIDGLGYVCKYATFGINQANAQKVKGGKRHQDMKMNTNNFSNEVINESDEDVLDSDSDSEIDSNDKMMRSYMYFMEDYENSENAIGKNQLPRKKYKDPSLTNPSLNTDYSWRKQFQPGQRPELFRIGKHALQVPTNVRNLGKKSTLNSENPYDNSSNLGESFINPTIMPDRDLGRNGVNGGKKEAGMLRMVKDYYKTSDIGR

atg9

Autophagy-related protein 9

953 amino acids

Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Required for mitophagy. Cycles between the PAS and the cytoplasmic vesicle pool and may participate in supplying membrane for the growing autophagosome. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. Different machineries are required for anterograde trafficking to the PAS during either the Cvt pathway or bulk autophagy and for retrograde trafficking.

Belongs to the ATG9 family.

107.554 kDa

MMTSNILSRFLPPNGSPSVYETIRHHDATSDSSDVEERAGLTLEDGSGEHYSDRELEDAMTDAERSRLLDPDDAFIRRKSPRKASVAGPSKSNSRHRHSGRPRWAHDASPGHDFEDGDDDVPASLLVEGHHDDDDDDLKSRLPPPPTSHFTPDNRQTSLPGPSTRGDRARWRAAREQQPLHHADRRRAPAVRWSLGQPNLNTVDPKEKAMWMWANVENLDNFLKDVYTYFLGNGIWSILLNRVLSLLTFAFVIGFTTFLTNCIDYHKVRGSKTLNDILIEQCTTKMSLSSTFLLWLLTLFWIGKAFQCLLDIRRLKHMHDFYYYLLGVSDTDIQTISWQEVVSRLMTLRDANPATAGAVSARHRKFMGSQSKQRMDAHDIANRLMRKENYLIALINKDILDLTLPIPFLRNKQLFSQTLEWNINLCIMDYVFNEQGQVRTLFLKDTHRKALSEGLRRRFIFAGIMNIFVAPFIVVYFMMHYFFRYFNEYKKNPSQIGSRQYTPLAEWKFREFNELWHLFERRINMSYPFASRYVDQFPKDKTVQVAGFVAFVSGALASVLALASIVDPELFLGFEITHDRTVLFYLGVFGSVWAVARGLVPEETTVFDPEYALLEVINYTHYAPSHWKGRLHSDEVRREFAELYQMKIVIFLEEILSMIFTPFILWFNLPKCSDRLIDFFREFTVHVDGMGYLCSFAVFDFKKGTNVINQGDRREPARQDLRADYFSTKDGKMLASYYGFLDNYGANHRGSHPATRRQFHPPPAFPTLGSPPAGEMGTIGDRLDQTQTRHGLAGPFMGQQSVFGPSRYGPTGLGDHASPAPSILLDPHHQPSTSGFRGTSRAAAFPRYRSSRAHPPTSGTIADGDESPVATGGSDPSRPAANAAGASSAGGVGTSDSNLGDSWRMNLAEDVDDDNTEGGENVDAIAGGAGVLGLIQQLQRVNKDTRGRTAVGL

ATG9

Autophagy-related protein 9

952 amino acids

Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Required for mitophagy. Cycles between the PAS and the cytoplasmic vesicle pool and may participate in supplying membrane for the growing autophagosome. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. Different machineries are required for anterograde trafficking to the PAS during either the Cvt pathway or bulk autophagy and for retrograde trafficking.

Belongs to the ATG9 family.

110.751 kDa

MSSSSYNPYKNNVNDRLINNSTDSFQDNDQGIPNNNDTFLSRIFGLNSIYNQLQDNYQYYDPEFDSSLNQQLQQSIQENDEAEDESLLPQHQQQQQQAAPMDLSIQDKSAKQKSKSSSLLNSDSDSDLSSSEDSYVRPNIPQIPSTPIETENQGSSSKIKFSIPQRAKNFVGKLHPHHEPTLPVYQTPQEFRRNLPQQQRASATVNTNYQRTRNNNRRFIIPPKERALYLWANITNMDEFLSDVYYYYRGRGLLNIVLSRGFDLIILIFILIFTVFLKWGIDYSIFFDNLHQEESKHITLNDMIIPNYFATIPLSIKFILFGFSVYILLRSVQLYLDYNYKLKELKNFYHYLLDVTDDELMTISWKTIVEKLMLLKDYNSLTSTTKSNNFSENHYVNDLSSKVRLNAHDIANRIMRRENYMIALINKDILDLSVLFMNEKSLLTKTLEWNLKLCIDNFIYNQQGQINGKILKEYNRNQLARELTSRFKLAAIINLILSPFIVIYFVLLYFFRYFNEYKSNPASILGLRQYTPYAEWKLREYNELSHLFNKRLIMSMGPANTYIDQFPKGFLVVNLMRLINFISGSILAVLVIMGILLEDENHSFWSFEITDGRSALFYISIFGTIWAITASSATGTSHESTISTTSQSSNSNSNSNAASTFVYDPEASLRYVAQFTHYLPSSWNKKLHTIQVKNEFCQLYCLKIIIIINEILSSVLTPFILWFKISHNSGNIIDFYREYSIHVDGLGYVCYFAMFNFEEKDKNMMSDLNKSKKRRKRMKNKMNKYGKTKMVNPISGKTVNSEIEMTKISKSESERSSDDESGNEQDYDNDEELDYLSYKKDDKMIKSYMYFLESYGGSKQPQPQPPQQQQHPQNQNQTVGGLRNRNPIQSIDPAIMTGNYYDQQSLNSSIYNINYKFDDSGLLQDETMNSSSRKKGGVLGMLNQFYKQDINR

atg9

Autophagy-related protein 9

951 amino acids

Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Required for mitophagy. Cycles between the PAS and the cytoplasmic vesicle pool and may participate in supplying membrane for the growing autophagosome. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. Different machineries are required for anterograde trafficking to the PAS during either the Cvt pathway or bulk autophagy and for retrograde trafficking.

Belongs to the ATG9 family.

107.356 kDa

MMTSNILSRFLPPNGSPSVYETIRNHDATSDSSDVEERAGLTLEDGPGEHYSDRELEDAMADAGRSRLLDRDDAFISRRSPRKASVAGPSKSNSRRRHFSRPRWAHDASPSHDFEDGDDDVPASLLVEGHHDDDELKSRLPPPPTSHITPDDRQPSRPGPSTRGVRGRGRAAKEQQPLHHADRRRAPAVRWSLGQPNLNTVDPKEKAMWMWANVENLDNFLKEVYTYFLGNGIWSILLNRVLSLLTFAFVVGFSTFLTNCIDYHKVRGSKSLNDILIKQCTTKMSLSSTFLLWLLTLFWIGKAFQCLLDIRRLKHMHDFYYYLLGVSDTDIQTISWQEIVSRLMTLRDANPATAGAVSARHRKFMGSQSKQRMDAHDIANRLMRKENYLIALINKDILDLTLPIPFLRNKQLFSRTLEWNINLCIMDYVFNEQGQVRTLFLKDTHRKALSEGLRRRFIFAGIMNIFVAPFIVVYFMMHYFFRYFNEYKKNPSQIGSRQYTPLAEWKFREFNELWHLFERRINMSYPFASRYVDQFPKDKTVQVAGFVAFVSGALASVLALASIVDPELFLGFEITHDRTVLFYLGVFGSVWAVARGLVPEETTVFDPEYALLEVINYTHYAPSHWKGRLHSDEVRREFTELYQMKIVIFLEEILSMIFTPFILWFNLPKCSDRLIDFFREFTVHVDGMGYLCSFAVFDFKKGTNVINQGDRRDPARQDLRADYFSTKDGKMLASYYGFLDNYGANHRGSHPATRRQFYPPPAFPTLGSPPAGEMGTIGDRLDQTQTRHGLAGPFMGQQSVFGPSRYGLTGLGDHASPAPSILLDPHHQPSTSGFRGTSRAAGVQRYRSSRAHPPISGTIADGDESPVATGRSDPSRPAANAAGASSAGGVGTSDSNLGDSWRMNLVEDGDDDNTEGGENVDAIAGGAGVLGLIQQFQRVNKDSRGRTAVGL

atg9

Autophagy-related protein 9

951 amino acids

Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Required for mitophagy. Cycles between the PAS and the cytoplasmic vesicle pool and may participate in supplying membrane for the growing autophagosome. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. Different machineries are required for anterograde trafficking to the PAS during either the Cvt pathway or bulk autophagy and for retrograde trafficking.

Belongs to the ATG9 family.

108.226 kDa

MMTSNILSRFLPPNGSPSVYETLRQQDAESNPSDVEERAGLEFEDDRRTQFSDRELEEAMVDAARDGIRSPSPSPSEPFLTQRSPQRTSGTATAKTGGRRRKHSRPRWMHQDPDDGDDDVPPSLLVEGHQDDDEMRSRLPPPPPSHRHPQRELSPAPGPSSRADRARWNTTREQLPLHNDGRGQRPGVIWSLGHPNLASVDPKEKAMWLWANVENLDNFLKDVYTYFLGNGIWSILLNRGLSLLTFAFVVGFSTFLTNCIDYRNFRGSRKMDDILIQQCTKKMSMSSTFLLWLLTVFWIGKAFQYLMDIRRLKHMHDFYYYLLGISDSEIQTISWQEVVSRLMTLRDANPATAGAVSARHRKFMGSQSKQRMDAHDIANRLMRKENYLIALVNKDILDLTLPIPFLRNRQLFSQTLEWNINLCIMDYVFNDQGQVRTLFLKDTHRKALSEGLRRRFIFAGIMNIFVAPFIVVYFLMHYFFRYFNEYKKNPAQIGSRQYTPLAEWKFREFNELWHLFERRVNMSYPFASRYVDQFPKDKTVQVAGFVAFVSGALASVLALVSIIDPELFLGFEITHDRTVLFYLGVFGSVWAFARGLVPEETNVFDPEFALLEVIDFTHYFPNHWKGRLHSDEVRKEFAVLYQMKIVIFLEEILSMIFTPFILWFSLPKCSDRLIDFFREFTVHVDGMGYLCSFAVFDFKKGTNVISQGGTGRRESGRQDLRADYFSTKDGKMLASYYGFLDNYGGNRPANPSSRRQFHPPPAFPTLGSPSAIEMGNIGERLERTQTRHGPAATFMGQQSGLGPGFGAAGFGDHASPAPSILLDPHHQPTASDFRTANRSALYPRFRSSRPVRPITDPIEDDNESPSAEIRRGAVKKSPHTTTGSSGGAIGTSDSNLGESWRMNLIGDELDKDTGEDGENVDEIAGNAGVLGLIQQFQKVSKDNRGRTTVGI

atg9

Autophagy-related protein 9

949 amino acids

Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Required for mitophagy. Cycles between the PAS and the cytoplasmic vesicle pool and may participate in supplying membrane for the growing autophagosome. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. Different machineries are required for anterograde trafficking to the PAS during either the Cvt pathway or bulk autophagy and for retrograde trafficking.

Belongs to the ATG9 family.

106.768 kDa

MMTSNILSRFLPPNNSPSVYEAIRQNDADSDSSDVEERAGLTLEDGHGGHYTDHELQDAMVDADQSELPSPDDAFLARESHHRVPSEGPSKSTSRRRKNSRPRWMQAASPGQDFEYGDDDDVPASLLVEGHHDDEDLKSRLPPPPRPLSPHEIQPSLPGPSSQGDQARWRAARDQQPLHNASRRRPPGVKWSLGQPNLNTVDPKEKAMWMWANVDNLDNFLKEVYSYFLGNGIWSILLTRVLSLLTFAFVVGFSTFLTNCVNYHKVRGSKTLDDILVDRCTTKMSLSSTFLLWLLTFFWIGKAFQCLLGIRRLKHMHDFYHYLLGVSDTDIQTISWQEVVSRLMTLRDANPATAGAVSARHRKFMGSQSKQRMDAHDIANRLMRKENYLIALVNKDILDLTLPIPFLRNRPLFSQTLEWNLNLCIMDYVFNEQGQVRTLFLKDTHRKALSEGLRRRFIFAGFMNIFVAPFIVVYFMMHYFFRYFNEYKKNPSQIGSRQYTPLAEWKFREFNELWHLFERRINMSYPFASRYVDQFPKDKTVQVAGFVAFVSGALASVLALASVVDPELFLGFEITHDRTVLFYLGVFGSVWAVARGMVPEETNVFDPEYALLEVINYTHYFPSQWKGRLHSDEVRREFAELYQMKIVIFLEEILSMIFTPFILWFSLPRCSDRLIDFFREFTVHVDGMGYLCSFAVFDFKKGTNVITQGDRREPARQDLRADYFATKDGKMLASYYGFLDNYGANPRGAHPSTKRQFHPPPAFPTLGSPSAMDLGHLGDRADPPQARPFAGQQSTFGPSRFGPTGLADHGSPAPSMLLDPHHQPSASGFRTAHRTAFSRYRSSRAAPPISGAILDDDESPSAPNRNGSARSAAGAPAPPGGSSGGGVGASDSNLEDSWRMNLTGDTDDEDAGAGGENADAIAGGAGVLGLIQQFQRVNQDGRGRTAVGL

atg9

Autophagy-related protein 9

948 amino acids

Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Required for mitophagy. Cycles between the PAS and the cytoplasmic vesicle pool and may participate in supplying membrane for the growing autophagosome. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. Different machineries are required for anterograde trafficking to the PAS during either the Cvt pathway or bulk autophagy and for retrograde trafficking.

Belongs to the ATG9 family.

107.622 kDa

MMSSNILSRFLPPTGSPSVYETIRQHDAGSEYSDLEERAGLVIEDQQEQYSDRELEDALADAQDSEIVSPSTALLNQARSVKAPEERASPSGTRRRKSSRPRWMAQESPLGYELDDHDEDVPQSLLVEGHHEDLKPRLPPPPQSHNRSDRRRTPSPGPSSRPTEARWNERGVHQQPPPSESGHPIGRWFTGQHPGLANVDPKKKAMWRWANVEDLDNFLKDVYVYFLGNGIWSILLTRVLNLLTFAFVVGFSTFLTNCIDYPKVRRSKTLNDILVPQCTANMSGSSTFLLWLFSFFWIGKLFQYLLDIRRLKHLHDFYLYLLGVSDAEVQTISWQEVVSRLMALRDSNPSTAAAVSAKHRRFLGSQSKQRMDAHDIANRLMRKENYMIALVNKDILDLTLPIPFLKNRQLFSRTMEWNLNLCVMDYVFNEQGQLRTLFLKDTHRRALSDGLRRRFIFAGVMNIFVAPFIVVYFMMHYFFRYFNEFKKNPGQIGSRQYTPMAEWKFREFNELWHLFERRINMSYPFASRYIDQFPKDKTVQVARFVAFISGALASVLALASVIDPELFLGFEITHDRTVLFYLGIFGTVWAFARGLAPEETDVFDPEYALLELIDFTHYFPSGWKGRLHSDDVRKEFAILYQMKIVIFLEEILSMIFTPFVLWFSLPKCSDRLIDFFREFTVHVDGVGYLCSFAVFDFKKGTNVLSQAGPGRRDPGKQDLRTDYFSTKDGKMLASYYGFLDNYGTTHQATSRRPFHPPPTLPTLGSPTAGGFGALPDRPDHLQTRLGPTPGAPFGPQSMIGTSKPRQMGGFDHRSPAPSILLDPHHQPSTTGFRAAARIAPQQHQRSRLGRSHHPSTDPIDDEEEPLSQDGHDSTTRQSGARTGTSSAGAGTSDSNLGDSWRMNPLSNDEDEGDEGENIDAIAGGGGVLGLIQQFQKANTEGRRTNVGI

atg9

Autophagy-related protein 9

944 amino acids

Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Required for mitophagy. Cycles between the PAS and the cytoplasmic vesicle pool and may participate in supplying membrane for the growing autophagosome. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. Different machineries are required for anterograde trafficking to the PAS during either the Cvt pathway or bulk autophagy and for retrograde trafficking.

Belongs to the ATG9 family.

106.967 kDa

MASNLISRLLPSNTQGRSIYDSLRAHDEASGSDMDVEERAAMAIDEENLRFKDDELGNPADVISGESVTESTAFLSDQQQTPQKQGYNRKGKGKGRSHNLAESPRLLEEDSDDDVPASLLIEGNNRHADPETPNHIRARQTALPKRAPAVPGPSAQQIKEERDRAHWEMTQEQQKLHEDGGNRATGVPHTPQSIPQNTGFYLTGSPKDKAMYRWVNVTNLDNFIGDLYAYFEGAGIWCIVLAKVIDILTLVFVAVFTTFLTQCVDYKKIYRGDARSLEYALVPQCTKKISGMSNVAIWLVCLFVLYRVYQLLTDLPRLMKMRDFFTYLLEIQDSNMQTVSFQDVIARLMALRDANPMTVERISPDNRKFVLGTQSKQRLDAHDIANRLMRKENYLIALFNKEILDLTLPLPFLQGRQLFSKTLQWNLEWCILDFVFNDYGQVRQLVLKDSHRRELSDGLRNRFLFAGLMNVICAPVIVIYVVIVYFFKYFNQYHKNPAALGSRGYTPLAEWKFREFNELHHLFNKRLNMSYPFASRYLNQFPNVKTAHMAKFITFMAGAVVSVLVVATVWDSEVLAGFDITSERPVLFYIGVFGSLWAITNGMIPEENEVFDPEYALRQVIEYTHYMPNHWQDRLHSDEVKREFSTLYQLKLMIFIEEVFSIIITPFLLWFSLPKCADQIIDFFREFTVHVDGVGYVCSFAVFDFKKGDGRAPTQGKAKSDMREDYYSTKHGKMAASYYNFLDNYLLNPKTGVPGHNPPGLRQQFYPPPAFPGLISSPTSGADLQSSRMGRSDVRPMNRAPYVPQQAVRTPRFPSNTTATGSPMASILLDPRHQPPSSELGARSVRRSSRSRYQARRGNNIIEDPMEDENGPGRPVAQPGRSYAVDDTVANLGESTWEVSPAKADADGQDEEEDGDGTGGAGVLGLVYQFQKAQTNGRPGVSIW

atg9

Autophagy-related protein 9

941 amino acids

Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Required for mitophagy. Cycles between the PAS and the cytoplasmic vesicle pool and may participate in supplying membrane for the growing autophagosome. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. Different machineries are required for anterograde trafficking to the PAS during either the Cvt pathway or bulk autophagy and for retrograde trafficking.

Belongs to the ATG9 family.

106.681 kDa

MMTSNILSRFLPPNGSPSVYETIRQHDNHSDASDVEERAGMAFEDEHGDRFSDRELEDALADAGRDDSPGPSEPFLPRSPPTKRDEGGFLKAGSRRRKFSRSGRIHAASPRHKFDDSDDDVPPSLLVEGDQDDDDVLRSKLPPPPRSIDPPNVEPPPRPSPRDDRVHWEAARDRLPLHDTNRRAHHASLWSAGYPNLALVDPKEKALWMWANVENLDNFLKEVYTYFLGNGIWSILLNRVLSLLTFAFVVGFSIFLTNCIDYHKVRGSRTLDDILIQKCTKQMSMSATFLLWLLSFFWIGKAFQYLLDIRRLKHMHDFYHYLLGISDAEIQSISWQEVVSRLMTLRDSNPATAGAVSAKHRKFMGSQSKQRMDAHDIANRLMRKENYLIALINKDILDLTLPIPFLRNRQLFSRTLEWNINLCIMDYVFNEQGQVRTLFLKDTHRRALSEGLRRRFMFAGIMNIFVAPFIVVYFMMHYFFRYFNEYKKNPSQIGSRQYTPLAEWKFREFNELWHLFERRVNMSYPFASRYVDQFPKDKMVQFAGFVAFVSGALASVLALASVVDPELFLGFEITHDRTVLFYLGVFGSIWAVAQGLVPEETNVFDPEYALLEVINFTHYFPGHWKGRLHSDDVRKDFAVLYQMKIVIFLEEILSMIFTPFILWFSLPKCSDRLIDFFREFTVHVDGMGYLCSFAVFDFKKGTNVISQGDTGRRDAARQDLRADYFSTKDGKMLASYYGFLDNYGANPRSGHPSTKRQFHPPPTFPTLGSPSAIEMGNFGDRPAAAGLMGQQSTYGAAPRFGPAGMGDHLSPAPSMLLDPHHQPSASGFRSTHRANPYPRYRASRPPPTISDPIEDEDPPAGKGRSAVKSSPGVGSSGGGIGTSDSNLGESWRMNLVGDEVEEEDEGGENVDTLAGGGGVLGLIQQFQKVNQDNRGRTTVGI

ATG9

Autophagy-related protein 9

931 amino acids

Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Required for mitophagy. Cycles between the PAS and the cytoplasmic vesicle pool and may participate in supplying membrane for the growing autophagosome. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. Different machineries are required for anterograde trafficking to the PAS during either the Cvt pathway or bulk autophagy and for retrograde trafficking.

Belongs to the ATG9 family.

105.882 kDa

MTSQLITRLLPINSTTSPSIYETIRQYDDDSGHSDTEERAAMAVDEENLDGAYQDYELEGALAQASDTQSTHSSFQSPAAGDSHLPRHPKWTQESVNEAEHDDEVPASLLVEGDGEEDPLPPPPRPPSNRNRILDDAPAAEFCSPRLRGQWEAAEEHQTPHLAPQPSPPLNLHSNRRAGLAFANPKEKAMWRWANVENLDNFLKDVYIYFIGNGIWCIVLSRMLNILTLAFVVGFTTFLTNCVDYRKVPHSKTLNQIIVPKCTNKMSASSTFFLWLFTVFWFGKVFQYIIDFRRLRHMHDFYLYLLDVPDSDIQTISWQEVVGRLMALRDANPATAGTVSTKHRKYIGSQSKQRMDAHDIANRLMRKENYLIALFNKEILDLTLPIPFLRNRQLFSRTLEWNLNLCILDYVFNEQGQLRPLFLKATHRRALSEGLRRRFIFAGVMNIFIAPFIVAYFLMHYFFRYFNEYQKNPSKIGSRQYTPLAEWKFREFNELWHLFERRIHMSYESANMYINQFPKDKTVQLSRFVAFIAGALLSVLALASVIDPELFLGFEITHDRTVLFYIGLFGTVYAVARGVVPDDAQVFDPEHALLDVTAYTHYKPAHWQGKLHSDDVRKEFATLYQLKVVIFLEEILSMIFTPFVLWFSLPKCSDRLIDFFREFTVHVDGLGYVCSFAVFDFKKGTNLMPPEPQHHRPRGLKHGLHDLRGDYFSAKDGKMLASYYGFLDHYAPPARPSGPHASQRQNYPQQPVPGPTHRAQPGANHLHSSRIDRWDNGQHSTMRQSALRTSRFGAITGVGGHASPMASMLLDPHHQPSMSGFRSKAHPTAASRYRPSRQAHPMADTIQDVDEDQLPGINIQPSNVTTTSSGGPATDDSQIEESWRINLAEDANSGEDDEAEDVEKVAGGGGVLGLIHQFQKVTNEGRGAVGM

ATG9

Autophagy-related protein 9

928 amino acids

Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Required for mitophagy. Cycles between the PAS and the cytoplasmic vesicle pool and may participate in supplying membrane for the growing autophagosome. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. Different machineries are required for anterograde trafficking to the PAS during either the Cvt pathway or bulk autophagy and for retrograde trafficking.

Belongs to the ATG9 family.

107.241 kDa

MEQSGHEPGKNTFLSRVFGLQSDDVSTSIHTQELSTIPLDEDESNHGALVESEDDEDHNDGVRLLESDPGTSTQDSLESDTSEEDERINGINSDSQVIDTSRPLLSKKETMELHPFGSQNGRIMESSIKLGQPSSDEEDLINVNESLQPDLENRINPIYHEDKLDKALGNSSKNIRTSTFLDRVLKPNDVKKNSTKKRQNSHNYNPTSTYTNSSSNTFLNTVKGEKSSKKYKLKRPNILNALSVVNNMPERRLNTLSPKERALWKWANVDNLDLFLQDAYNYYLGNGFHCIILQKVLNILTLLFVVFVSSFMGYCVDYSKLPTSTRFSEIKIDHCYSQNITGFTKFLLFLFYGFVILKVIQLYFDINNIREMKLFYHYLLNISDDELQTIPWQNIIQQLMYLKDQNALTANVVAVKAKNKLNAHGIANRIMRKENYLIALYNNDILDLRFPIPFFGSQPLTKTLEWNINLCVMGYVFNEAGFIKQGFLKATQKEYFANELRKRFMLAGFLNIILSPFLVSYFVLLYFFRYFNEYKTSPENIGARQYTPMAEWKFREYNELYHIFRKRIGLSNPLASKYVDQFPKEKTNILLKFVSFISGSFVAILAILALWDPENFLNFEVTHDKTVLFYITVLGAIWSISQGSVSTEYHVFDPEETLRELAEYTHYLPDSWKDRYHTEGVKQEFCELYNLRITVLLRELASLITTPFILWFSLPNSAGKMVDFFRESSVYVDGLGYVCKYAVYDGDADAVKKHFGTDGNETTEQDAATEEQDIDSEPDEATKKMMQSYMYFLDDYENDDNLLGKYQIPKKRRESFDNTQYDVSNSNQKNQDDDSDMILANRYTWRKQFKPGQKPELFRIGNHVLNDKTFTQQGSNHLGIDESYARSQISNTAEESNRSSLYNSKYKSPTKGVLGLVKEYYKKSDVGR

ATG9

Autophagy-related protein 9

917 amino acids

Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Required for mitophagy. Cycles between the PAS and the cytoplasmic vesicle pool and may participate in supplying membrane for the growing autophagosome. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. Different machineries are required for anterograde trafficking to the PAS during either the Cvt pathway or bulk autophagy and for retrograde trafficking (By similarity) (PubMed:30776962). Plays a role in appressorium formation and pathogenicity (PubMed:30776962).

Belongs to the ATG9 family.

104.559 kDa

MASNIFSRLVPQDRGRSFYEDLRQTDPDADLESRAGIDIDEENLNRSYHDYDLDEAERLAGDESHISHSRGDVAGANTVHRRGQKANTARWLGAGVEDDVDNDVPESLLVETPRAPQHLLLSPSRAGPSHPRPTAVPGPSTRQNQAQWEATRHQQRLHNDDTMPHGPFSGRAGQGRPEPPPVGLMAGDPYEQAMWRWVNVSNLDNFIKDVYAYYRAAGFWCIIVQRILELVNAAFVAVFLTFLSQCVDYHKLPHSKKMEDIIIPKCTQNMSLVWNVGLWLFAIYFICRCFGLIIQLRQLKHLRDFYTHLLKIPEADMQSVSWQDVVGRIMALRDSHPRTAGNLTRVQRAWIGSQSKERLDAHDIANRIMRRENFMIAMLNKDVLDLTIPLPFFRNKQHMSECVVLAISFSILDFVFDNQGQVNPEFLKASRRRQLSQKLKSRFFFAGLMIFVMSPFIALYLILVYFLTYFHEFRNDPGALGARTYNSLAKWKFREFNELDHLFNDRMNMSHPFAKRYIDMFPKRKTEQVARTVSFITGSIVAVLGLATIFDSEAFLTFEITPDRSVLFYVSILATLWAVARGNISDDNEVYDPEFAMKSIIEFTHYEPDHWRGRLHSTEVKNEFSELYKPRPQIFLEEILSILLTPLVLLVSLPNSTDQIVDFFREFTIHVDGLGYVCLFSVFNFQQGHANQKQAAAADAPDNREEYYSTKHGKMAASFYGFLDHYVINPKTGLPGNQLPGSRQQFQHPPSFPGLQSPTLAADMRHSRMMRERGRSSGVQIQGSQGRTPQFRTPMPQPSPMASILLDPHHQPAPGAFGSRSMHRSRQMAVPHRGGYMSDRDIIEEAVTEDGQDDARFGKLGDEDIDESGGALDESTWQTSPTKTLSRENSGANPQETEVGVLGLIHQFQQAHMHLRR

ATG9

Autophagy-related protein 9

916 amino acids

Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Required for mitophagy. Cycles between the PAS and the cytoplasmic vesicle pool and may participate in supplying membrane for the growing autophagosome. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. Different machineries are required for anterograde trafficking to the PAS during either the Cvt pathway or bulk autophagy and for retrograde trafficking.

Belongs to the ATG9 family.

105.558 kDa

MSRNSPLQSGQRGPPNGSPYPDSSQNNDTFLSRIFGLNSVYNHLQENYQYYDPEFDSTYNQQVLANSQRQDYDLFGNGLDKTNLLDSESDSDLSSSSSASPSVVVKPRFKRTEASDNEDDEVDDLLTSLSKPRSSPPRRKPTFNIPNARDIFSANGNTQATSVLPLYNQKYRKPVERDTGASAGDSRGYANSGIRRTNGTRFVIPPKERALYLWANITNMDEFLTDLYYYYRGKGMLNIVLSSIIDLLILVFILGFTVFLKWGINYRYFFDNYKDSTYITLADLIIPNFLVDEVPLLAKFFLFGFVCYIVLRLIQLYFNYNYKLKEIKNFYKYLINISNDDELMTITWKTIVERLMLLKDYNSLTSTTSHFDGATDHYINDLNSKVRLNAHDIANRIMRKENYMIALINKDVLDLSLSPFQNSSFQLINNKSVLTKTLEWNLKLCINNFAFNNEGQINPSILKDFNRNQLAKELNSRFKMAAIINLILCPFIVIYFVLLYFFRYFNEYKSNPASIMGLRQYTPYAEWKLREFNELPHFFIRRLQLSVGPANTYINMFPRGFLVINLMNLVNFISGAIMAILVIMGLWFEDENHSFWSFELTEGKSTLFYISIFGTLWAITSTSTSTSDTADNLNPNSHSFVYDPEASLRYVSQFTHYLPSSWNRRLHTVEVKNEFCELYSLKIIIILNEIFSLILTPFILWFRASSSSGAIIDFFREYSIHVDGLGYVCYFAMFNFEEKDKNMMFDLNKRKGKSKRSRRSKTSKTSSKKTVNEIELNNIKSKRREKAKISDSEDASSLPNTSDDESGNDLNADTYQDEKMIKSYMYFLESYGAGKADVRAINSNNKLLAKNSVISNIDPSPSLIIQGPSDNHSLLDSAYNINYKFDDAEQEESTRPGKKSGVLGMINQFYKQDLGR

ATG9

Autophagy-related protein 9

908 amino acids

Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Required for mitophagy. Cycles between the PAS and the cytoplasmic vesicle pool and may participate in supplying membrane for the growing autophagosome. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. Different machineries are required for anterograde trafficking to the PAS during either the Cvt pathway or bulk autophagy and for retrograde trafficking.

Belongs to the ATG9 family.

104.039 kDa

MTDSQDKVNGGSKNTFLSRVFGVHSSAVENSLDAAEMSHITMPTEQDFSNYAEDEGNVRLIESDQEPSSSNEDSNDEEPLIQQPQSIRFDTASDGMATIQSESEPDEGGTEEDEVHLEEEDFSDQDLASSVSKYGQPSSSEDEEPLSNRDSNRGSDETIPFIGRQRLNLGGKNPITGATKSTKNPSESRVFERLLGNSPAKMFRNNGRPNNLEESFLFRKPSVAEQSGPGKSTHFNLKPPPIFNNISTLTSTSKNSLSSLSPKERALWKWANIENLDTFLQQVYEYYLGNGFYCIITEKVIHLATILFVVFISTYMGHCIDYSRLSSSHTFEEIHIEQCYKTQISPTAKVFLWIFYAFIGLKVLQLYFDVKALKDIRNFYNYLLSISDKDLQTIPWQSVIQQLVLLKDQNAITANATEVKAKNRLSAHDVANRIMRKENFVIALYDNNILDLSLPVPLLRTCALTKTLEWNINLCILGFAFNEKGYLKQAFLRESQREYLGEELKKRFVLAGFLNIILSPFLVTYFVLLNFFRYFNEYKTSPGSIGSRQYTPIAEWKFREYNELYHIFQKRMRLSMIIADNYVNQFPNTLLSLTLSFIQFVSGSFVAILGILTIFDPDNFLNFEITPDRTVLFYMTVFGTLWAVCHSSINDEYTVLKPEETLEELVSYTHYAPKEWKGKYHTEDIKNEFCRLYNLRITLLLRELVSIIITPFILWFSLPKNSERIIDFFRECTVYEEGLGYVCKYAMFEATKIDKGTKAKKQTKRMFSQAEQDDSETESDEGVNKMLQSYMYFVDDYKNAGNAVGKNQLPASPIEPSYHPYSSTKDYSWKTQFALGKNSNRKRNLNRSRVKRFPDRSSDLELGSLSGSLINKSTLFKDDIADNADELKAGNGVMGLLNQYYKKSDRNR

ATG9

Autophagy-related protein 9

906 amino acids

Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation (By similarity). Plays a key role in the organization of the preautophagosomal structure/phagophore (PAS) assembly site, the nucleating site for formation of the sequestering vesicle (By similarity). Required for mitophagy (By similarity). Cycles between the PAS and the cytoplasmic vesicle pool and may participate in supplying membrane for the growing autophagosome (By similarity). Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress (By similarity). Recruits vesicle-tethering proteins TRS85 and YPT1 to the autophagosome formation site (By similarity). Recruits also ATG23 and ATG8 to the PAS (By similarity).

Belongs to the ATG9 family.

103.936 kDa

MVDNQDNVNEPPKNTFLSRVFGVHSSAVENSIDGAEMSHISIHNSQEFNHFVENEHHERLIESDQESSTNEEESNDEEPLIKQPQSIRFQEVPNGIAITHPFSESEDDEGEIEGRDPEFFSDQDLGSSISKHGQGSSSEDESEQAPTGDDAGPIGFERNSPIVENTRLGFHSPYDANSKANLKGPYLGHSKVFDRIFANKPAGMSRNRRHDDLEESFLFRKPSVADPRSTKTPAPFNLKPPPIFQNVPNLTSVNKNSLSTLSPKERALWKWANVENLDTFLQQVYDYFLGNGFYCIIVDKVVQLATILFVVFISTYMGHCIDYSRLSSSHSFKEVHIEQCYKTQISPTAKVLLWIFYAFIGLKILQLYFDVKALKDVQNFYNYLLGISDKDLPTIPWQSVVQQLVLLKDQNAITANATEVKAKNRLSAHDVANRIMRKENFVIALYDNNILDLSLPIPLFRTCALTKSLEWNINLCILGFAFNERGYLKQAFLRESQREYLSEELKKRFVLAGFLNIILSPFLVTYFILLNFFRYFNEYKTTPGSIGSRQYTPIAEWRFREYNELYHIFEKRKKLSMVIADDYISQFPNTLMSSLLSFVQFVSGSFVAILGILTVFDPDNFLNFEITSDRTVLFYMTLFGSIWAICHGAINEEYTAFSPEETLRELISFTHYSPKSWEGKYHTEDIKEEFCKLYNLRIILLLKELVSIILTPFILWFSLPKNSDRIIDFFRECTVYEEGLGYVCKYAMFDGAKVNKGLNAKTQASKMFSQTDNDDESDSDNDIGVNKMLQSYMYFVDDYKKAENALGKNQLISPKEGSFGYPRDYSWKTQFALGKKINKRSGEGPSQRRNLEHGSANPDVGSLNASFINKSSLYKDDFTENTDEMKKGNGVMGLLNQYYKKYDNKR

ATG9

Autophagy-related protein 9

905 amino acids

Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Required for mitophagy. Cycles between the PAS and the cytoplasmic vesicle pool and may participate in supplying membrane for the growing autophagosome. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. Different machineries are required for anterograde trafficking to the PAS during either the Cvt pathway or bulk autophagy and for retrograde trafficking.

Belongs to the ATG9 family.

104.615 kDa

MSEYNQNSNNDTFLSRVFGLHSVYNQLQDEYQYYDPDVDYQQSFMNGGVLSSHVREEGNENTNNDNTNLLDSESDSDSSSSLSSPPSPIVSFTGKEHNQNEDSTKVHWDTTRPHYGQDNDITTSIPKDPPKKNMVNTAKNFINKLHPATDSLPMYNQPQQFRKPPPEGPSVQTVYQKKQHKSKRKYVIPPKERALYLWANITNMDEFLTDVYYYYRGNGMLNIVLTRLVDLLILAFILSFTVFLKWGINYDFFMSSSSDRASVTLKDLVIPNFISEMVPVSVKLLLLGFSGYIVLRLVQLYFDYNYKLKEIKNFYHYLIGIPNDDELMTISWIVIVERLMALKDYNSLTSTNTNLPAQFLSDLNSKVRLNAHDIANRIMRKENYIIALINKEVLDLSLSIPFLSNVNSFLSNKSVLTKTLDWNIKLCINNFIFNQHGQINSHVLKDFNRNQLSKELSARFKMAAIINLLLCPFIVIYFVLLYFFRYFNEYKSNPSSILGLRQYTPWAEWKLREFNELPHFFIKRLHLSIGPANIYINQFPRGFWVINLMNFVNFVSGAITAILVLMGLWFDNEEHNFWSFEITENKSSLFYISLFGTVWAITSSSLTSTNSNTSENLNSQTSSFFYDPEASLRYVSQFTHYLPSSWNGRLHTVQVKNEFCELFSMKIIIIINEILSLILTPFILWFKVSNSSGAIIDFFREYSIHVDGLGYVCYFAMFNFEQKDKNMMMSLNKSKKRKPRKSRANAKKKASSKSKSRSDEIELDNVNSNKADKSKLSDSETSSNSDDNDDTDINNDYYQDDKMIKSYMYFLETCGNDKAKQASKLTSNEQLSTKPSRIAKPDNSQSVVGDPTPSFLYQPLTSNSIDDSSYNINYNIDEQEEESSKGKRSGVLGMINQFYKHDRNR

ATG9

Autophagy-related protein 9

900 amino acids

Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Required for mitophagy. Cycles between the PAS and the cytoplasmic vesicle pool and may participate in supplying membrane for the growing autophagosome. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. Different machineries are required for anterograde trafficking to the PAS during either the Cvt pathway or bulk autophagy and for retrograde trafficking.

Belongs to the ATG9 family.

102.673 kDa

MPRKLFSKMPTTQGRSFYEELRGHDSEGYDGGSRAGLLDEENLNHNFQDYDLDHAEGLTVDDSRATLAGLRKTPASKVPPGHQNDRSMWLAHDDDADNDVPPSLLVEPRGAHLAGKPKRKQSRQAAYTMPGSSNTRAQWETIQAHQPLHNDEPFTQSHRGNGAPGSLFSGSASLDAKKMAEWRWANVQNLDKFIKEVYDYYRGCGIKAIITERVLHLGNVAFIAVLLTFLTQCVDYSLVRGSQKLSQIIVPQCTRKMSGWWNLGLWLFAFYFIWKAIQYILDLHRLFHVRDFYTHLLNIPDHDMQTITWQEVVARVMALRNQNSKTATTLTPLQRHFIGSQSKERLDASDIANRIMRRENYLIALFNKDILDLTIPLPFLRNRQYFSRTLEWTLMFSVLDMVFDEKGQVNQKFLRADRRGEISEKLRSRFQFAGIMILVLSPFVSLYLVIYYFLMYYHEIQKNPSVLSSRSYTPLAEWKFREFNELPHLFQKRLDMSKAFATHYMDQFPKVKTEMVAKSVAFVSGALATVLAIASVFDPELFLGFEITPDRTVLFYTAIFGSIWAVAHGMQSQDDVVFDPEYAMRNVIEYTHYEPDHWKDRLHSYDIKLEFAELYKPKIVIFLEEILGILTTPFVLFFSLPKCSDQIIDFFREFTLHIDGLGYVCTFAEFDFKKAMANAKKPSDGGDVRDEYYSAKHGKMEASYYGFIGNYGNFALNPKGAPGSHLPPGMRNQFHPPPAWPGLNSPPLGADMQTSRMGRSEFRSRSRAPGQGLRPGPSMVAPSPMASILLDPHHLPPSHLVNPGRASHPHRVQQNRRPGESNIIEESLEDEERGREGVNRHDDEEVYGHGDGMDESAWQTSPARTLSRDNSAIEGTGTAEAGVVDMIYQFNQAQFTRNGV

ATG9

Autophagy-related protein 9

899 amino acids

Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Required for mitophagy. Cycles between the PAS and the cytoplasmic vesicle pool and may participate in supplying membrane for the growing autophagosome. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. Different machineries are required for anterograde trafficking to the PAS during either the Cvt pathway or bulk autophagy and for retrograde trafficking.

Belongs to the ATG9 family.

101.537 kDa

MASNLLSRLLPSASDDLLEQEASNNQNRRTSSSTDERPDMDIDEENFGARFEAQDLNDLLAEASSSHMTTESRAASPEARRNAPPGINTAARAPAWRQPAPARAVPLDDDDDVPQSLLLEGGLDPPPNPHPRPDGLPPPVPGPSTRHTRAQWETTRQQQRLHGDDRGGAPVRDWGAIGRGGQFTADPKEKASWLWVNQTDLDTYMREVYEYYVGSGIYSMILRRTLSLLQSAFVVGFMTFLGWCIDYSKLSGSNKLSQVLVPKCTKEIHGFWIFALWVFTIYWLYSFYGLLTDIPRLRAMHDFYHYLLDVPDRDIQTIQWQQIVSRIMALRDLNLTTASNLSPETRKLLDSKSRQRLDAVDIASRLMRRDNYLIALFNKEILDVTVPIPFLGNRFIFSETTGWHVNLAVMEFVFSGPNGQFNQDFLKERNRRELVRRLRGRFFWTGIISIICAPFAVVFVLASYLFKYFTEYHKDPGQLSNRDFTTFAQWKFREFNELPHLFNRRRNMAYPYANLYLAQFPKDKTEQISSFVAFIAGAFASVLVAFTLLDSELFLTFEISPGKTAIFWIGVLTTIYRVARGSSPQEDQVTDPSYYLDHVIYHTRYKPDSWQDRLHTDEVRAEFAKLYQPKILIFAEEILSMVVTPFLLMFRLPQCSERIVDFFREFSIVVDGLGVTCSYSMFPFKKGTQNVNNAPANRSGAHKDDGDLREDYFMAKDNKMLASYYGFLDTYATTGKGNSARLPGRAGFHPPPQFPNAFGAMSQTAQPVDVGARGTSRGPAGRQPLQRRTPRSGPAGRDEPIASVLLDPHHQPSSASILRGSPRTGPSGRYRTPLQPVADTPGTRIEEESTIGDSWRTSRLAQDDDEEEEAPGANRGGVLQLLQQFSKAQAEGRGAGVGV

ATG9

Autophagy-related protein 9

897 amino acids

Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Required for mitophagy. Cycles between the PAS and the cytoplasmic vesicle pool and may participate in supplying membrane for the growing autophagosome. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. Different machineries are required for anterograde trafficking to the PAS during either the Cvt pathway or bulk autophagy and for retrograde trafficking.

Belongs to the ATG9 family.

102.811 kDa

MEQSEDTIQHERKNTFLSRVFGVHSSEVGDSIETAELSQYPIQIARSGSNAIDESRVIESDQASSSEEEDTDGHDLSVAENMTSYNGAQGSGSEDSDVPFSDQELETIETYTIAKVGQGSSSEDDRLQADSAEEEDALLFQHRLQDGSKGRNKVSSQPLGLKRILGSKGKSILGKEPASQEDSFIFRKGPTWDEENQLRPESKRPGLLSGKSNARLSSPSRPSPLSARERALWKWANVENLDGFLQDVYSYYLGNGFYCIMIEKILNLLTLLFIVFISTYMSHCIDYSKLPNGHKFSDVRVDQCYETQITGTTKLLFWIFGVFVVLKVVQMYFDFRRIHEIHNFYTYLLNISDKELQTIPWQSVIHQIMRLKDQNAVTANVVEVKAKNHIDAHDVANRIMRKENYLIALYNKDILHLSLPIPLYRTSTLTKTLEWNIHLCIIGFAFNEAGFLKQSFLNPAQREFLSEELKKRFILAGFLNIILAPFLVVYFVLLYFFRYFNEYKTSPGSLSTRQYTPIAEWKFREYNELYHLFKKRMGLSYEVANTYINQFPNALGDYFFKFVKFISGSFVAILALMTVLDPENFLNFELTADRTVLFYMTVLGTIWAVCHSAVNDNCSVFDPEDSLKELITYIHYAPKEWDGRYHTDEVKQEFCKLYNLRVILLLRELASLIMTPFILWFSLPNSAESIVDFFREVTVYGDGLGYVCKYAMFDENCKKGLRTNKHLQGTQTKYGHSLGDDHDSSDEETDKGMNKMIQSYMYFVDDYQNSVNAVGKYQIPKTQNLSHESKYNMKSHQHYSWKKQFKLGSKPEDFKIGSVTPRALSSSILANKPKSNLRARLDPEISHSNVQFDDLGESFINSIPVADYDPIERSDAMGGNGVLGLLNQYYRKSDVGR

ATG9

Autophagy-related protein 9

889 amino acids

Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Required for mitophagy. Cycles between the PAS and the cytoplasmic vesicle pool and may participate in supplying membrane for the growing autophagosome. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. Different machineries are required for anterograde trafficking to the PAS during either the Cvt pathway or bulk autophagy and for retrograde trafficking.

Belongs to the ATG9 family.

102.069 kDa

MGDLNKHTFLSRVFGSASNPLLNDDNNDIEFSINNLQDTFEEHQVESPPRAPHPINVNSEDESSSETESASNEDLLYDQKRELYQQVESELRQDDYDTVPESLMMERRRPHEGSTRTIGTKIPPSPAEPPIGPNITQWGEKARGIASRTLDNIPKTIAKGISFQLPANASSKLPPPPLSYRRETSVGGETEMAQNINEQRQLRGRLGLLSPMERALWLWSNVSNLDTFLEDVYGYYTGNGYRCIILSRVSDLLIIVFVVWLTSFMGNCVDYNQLMNGNATKYSDVVVDKCYSKISLSQKLFFLVLFAILVLRIKSFYSHFKDLKEIKNFYNLLLGVSDEELQTISWSTIVKKIKVLRDQNTNALISGNQNLRGDDLKSKKRLSAHDIANRLMRKENYMIAIFNKNVLAPALTIPFINHHFLTKTLEWNLKLCIFDFVFNTDGQLKQAVLSEHKRLALATEMRKRFRLAGILSIFLTPFLVIYFLLYFFLKFFYDIKTNPSLVGSREYSPYARWKLREFNELPHMFDKRLKMSRARATEYINQFPKEATNIILNFVAFVTGSLVTILVVLTVLGHENFLNFELTEGRTVLFYISTLGAVFTICKGSVSENDTVFDPEASLRYVAQFTHYLPNSWNGRFHTEEVKNEFCKLFNLRLILVLKEITSLIMLPYILYCRLPDVSEKVIDFFREFSVHVDGLGYVCTFAMFEFDSKDKPVRSQAANDDDDLKQEYYTADDDKMVKSYLYFLESYGNESVRKTGKEPAVDRISRRPGKKNLLRSAMMNNSMMDKSRGAQSTVRYPPQFRSPNLAESVYTKRQNIDLMEDTTAGLSTDTRNYLQTLNNSTLLGESFQHGFPVEDTTHHEEDADSEDDDEAGVLGLINQIYKHKEGVN

ATG9

Autophagy-related protein 9

888 amino acids

Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation (By similarity). Plays a key role in the organization of the preautophagosomal structure/phagophore (PAS) assembly site, the nucleating site for formation of the sequestering vesicle (By similarity). Required for mitophagy (By similarity). Cycles between the PAS and the cytoplasmic vesicle pool and may participate in supplying membrane for the growing autophagosome (By similarity). Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress (By similarity). Recruits vesicle-tethering proteins TRS85 and YPT1 to the autophagosome formation site (By similarity). Recruits also ATG23 and ATG8 to the PAS (By similarity). Autophagy is required for proper vegetative growth, asexual/sexual reproduction, and full virulence (PubMed:28894236). Autophagy is particularly involved in the biosynthesis of deoxynivalenol (DON), an important virulence determinant (PubMed:28894236).

Belongs to the ATG9 family.

100.819 kDa

MASNIFSRIKSPSGGSQSFYQQLRSGEDPEYDPGLDEENLGHRFDDFQAEGMDIGDSSMTVESVAPGSKGKGKATFRPTAHARSSGITSPRWQQDDDGDNEVPASLLMEPKDLDPPASPPNKRATNPGSSRTPASVGPSSARTRAQWEAATAQQQLHQDHPYTTPMGPQPIPVARGTMSNNPREKALWRWVNTSNLDSFMRDVYDYFEGGGLWCILCANALWLFQCIDYSRVPDSRSLHEVIVPQCTRKMSGLWNFAIWLYTFFFIWKCVQYFVEIRRLTYIRDFYIYLLDIPEQDMQTISWQDVVARIMALREENPKTATNISPRLRQFMGSQSKERLDALDIANRLMRKENYLIAMINKDILDLSLPVPFLRGRQMFSKTMEWYLQYCILDMAFNELGQVQQDFLRPDRRRLLSQKLRQRFLFAGFLNLLFAPVVLAYVVIVYFFTYYYEYQKDPKQAAARKYTSLAEWKFRQFNELPHIFYERLHMSYPFATRYIDQFPKRITEAVARTIAFMSGAITAILAIGSVLDSELFLNFEITKDRPVIFYLGVFAAIWATTRGMVSEETLVFNPEYALRNVIEYTRYVPDHWKNKLHSSEVKQEFSELYKMKVVIFLEEMMGIVTTPMLLLFSLPRCSDQIVDFFREFTIHVDGLGYVCSFAVFDFQKGPGNTGPQGPRPDVREDYYSTKHGKMAASYYGFLDNYAANPKTGIPGHLPPGPKPSFHPPPSFPGIGSPTLAADMQGSHIGRTGTETGRARSRAPGGRGPRIGVMPQPSPMASMLLDQHHQPPGGNMVARSLHASRYPRGYRGESQIIEETEASSIRRNGEDDELYEPGGALGESVWETSPARGVTRENSAANTEDPEAGVLGLIYQLQQTQRPRRGGGMV

ATG9

Autophagy-related protein 9

885 amino acids

Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Required for mitophagy. Cycles between the PAS and the cytoplasmic vesicle pool and may participate in supplying membrane for the growing autophagosome. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. Different machineries are required for anterograde trafficking to the PAS during either the Cvt pathway or bulk autophagy and for retrograde trafficking (By similarity). Essential for the formation of the sequestering membranes and assembly of the micropexophagy-specific membrane apparatus (MIPA) which mediates the fusion of the sequestering membranes and incorporation of the peroxisomes into the vacuole during micropexophagy.

Belongs to the ATG9 family.

102.597 kDa

MHKNNTTFLSRVFGINSRNIDVHNPLFADDSVIPLYDQNQSAYYDNAYSDYSSDEEDSKPRTSRQTDSNLHMTDHSGDGNDPFNQMDNSSRFSNSSSFHYNNTDQEDDNPELLLLQDEDSSLNRKNLDNSDFQSFAKKTFNQIPKIKFQLPKKEDYPTSHRQPPDIENQNGTLKSSVKKQIHFLDPMDKALWMWSNVSNLDTFLHQVYDYYTGNGFNCIMMNKFTELFTVVFIVWLFSFMGNCIDYDKLMNDRNVYQFSQVKIDKCYSKIGFFPQKLIYWLFFIGLCLKLYQIFLDYLVLKDMKLFFNLLLGLSDDELQTISWGLVVKRIMILRDKNINAIVSQNTDLTSRKRMNAHDIANRILRKENYMIAMYNKSILDLDIELPLIGKVQLLTNTLQWNLNIAILDYFFDSETGQINLPALKERNRHTISTELKKRLIFCGIINIVLAPILSIYFIMYYFLKFFYDFKTNPADISSREYSPYARWKLREFNELPHIFNRRLNISTESSNKYINQFPKETTTALLKFIMFISGSIVGVLVIVTILDPEFFLNFELTPGRTVLFYVSTLGAIFTICKNSIPDDTLVFDPEVSLRYLSQFTHYLPQEWEGKYHTEEVKNDFCKLYTLKLYLVGKEILSWLFLPYILCYKLPECADTISDFFREFSVHVDGLGYVCTFAMFQFNNQHNENGNANVHQNGNGNGGVPSAKSKSKKVPNPNRFTTKPSMRDMENDDKMIKSYMYFLESYGNDEIVQHQQALNRSLIYSTEISPTSGDDLNDSNILGLRQRNVATTGKRQNSIGNGLIYNGQNKRLSIGEAKTNVYSNPIASTVLDKDLQYKLANSYILNGMPGLNEANQPADRKNERKYSNDSPGVMKLVDKISQQHKA

ATG9

Autophagy-related protein 9

879 amino acids

Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Required for mitophagy. Cycles between the PAS and the cytoplasmic vesicle pool and may participate in supplying membrane for the growing autophagosome. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. Different machineries are required for anterograde trafficking to the PAS during either the Cvt pathway or bulk autophagy and for retrograde trafficking.

Belongs to the ATG9 family.

99.29 kDa

MGKGEGYLDPTILSVASGSRNSGKGKERTRRKGGHKYHSLHVQDEEEEEPPESDALRTRGKVGLNAYEKALWKWVNVDDLDGFLQEVYDYYKGKGIYCIVLARVLNLLTTFFVIAFSTFLISCIDYSKLFSSISTAEAVGRLEDVLVAQCITKFVHFKLYILNKTNSSAYDYRGSFAHTLFLIILSAFFIFQVASFAMSVPRLLDMYRFYTHLLGVPDADIQTLPWPEIVRLIGDIRKHNPVTSLSNGQATALADMVGNDAKAPAKKLDAHDIANRILRQENYLIALFNKDLLDLRVRIPVPHVLTAFIPSSILISSADAPLPSLQSEPERKFLSFGANHLTKALEWNLRFCLLGYLFDRRGQVRKEFVREKRRKDLVQGLRRRFIFMGILNAIFAPFIILYLLIYSFFRYFEWKFREFNELPHLFERRLDRSYEIAKEYVDQFPKERTALVMRFVAFIAGSFAAVLLVASLIDPDLFLHFEITPHRTVLFYLGVFGSILAISRGMVPQENMVFDPEASLNEVVRWTHYLPVEWRGQLHSQMVHQEFSKLFALKIMIFFSELLSVILTPFILFFSLPPCAAAIIDFFREFTVHVDGVGYVCSFAVFDFARYGNVDANQPETGLEGATGPDGGPAADGFAAGKPSRPTTRRTTSSSPSRLKHRDWRGNENKMEQSFLHFKATHPDWQPSDPSSSLFLDRLMGAGTRNRHGGGPVSAATGGISGSIYGGGGGGVGGRGLGVDGSVMAEMEEERLRAKRQSYERAWAKSSHLHRPDSSHSHPLRHPHSAASEIIEEEEGGEGDKGDDSIDGWSKRVKTDGETDDEEERERLWKDEGVIIIFFLTNNHITVVVMNVCRCIFRVAADEHKTAGRINKSQTRRLT

ATG9

Autophagy-related protein 9

879 amino acids

Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Required for mitophagy. Cycles between the PAS and the cytoplasmic vesicle pool and may participate in supplying membrane for the growing autophagosome. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. Different machineries are required for anterograde trafficking to the PAS during either the Cvt pathway or bulk autophagy and for retrograde trafficking.

Belongs to the ATG9 family.

99.29 kDa

MGKGEGYLDPTILSVASGSRNSGKGKERTRRKGGHKYHSLHVQDEEEEEPPESDALRTRGKVGLNAYEKALWKWVNVDDLDGFLQEVYDYYKGKGIYCIVLARVLNLLTTFFVIAFSTFLISCIDYSKLFSSISTAEAVGRLEDVLVAQCITKFVHFKLYILNKTNSSAYDYRGSFAHTLFLIILSAFFIFQVASFAMSVPRLLDMYRFYTHLLGVPDADIQTLPWPEIVRLIGDIRKHNPVTSLSNGQATALADMVGNDAKAPAKKLDAHDIANRILRQENYLIALFNKDLLDLRVRIPVPHVLTAFIPSSILISSADAPLPSLQSEPERKFLSFGANHLTKALEWNLRFCLLGYLFDRRGQVRKEFVREKRRKDLVQGLRRRFIFMGILNAIFAPFIILYLLIYSFFRYFEWKFREFNELPHLFERRLDRSYEIAKEYVDQFPKERTALVMRFVAFIAGSFAAVLLVASLIDPDLFLHFEITPHRTVLFYLGVFGSILAISRGMVPQENMVFDPEASLNEVVRWTHYLPVEWRGQLHSQMVHQEFSKLFALKIMIFFSELLSVILTPFILFFSLPPCAAAIIDFFREFTVHVDGVGYVCSFAVFDFARYGNVDANQPETGLEGATGPDGGPAADGFAAGKPSRPTTRRTTSSSPSRLKHRDWRGNENKMEQSFLHFKATHPDWQPSDPSSSLFLDRLMGAGTRNRHGGGPVSAATGGISGSIYGGGGGGVGGRGLGVDGSVMAEMEEERLRAKRQSYERAWAKSSHLHRPDSSHSHPLRHPHSAASEIIEEEEGGEGDKGDDSIDGWSKRVKTDGETDDEEERERLWKDEGVIIIFFLTNNHITVVVMNVCRCIFRVAADEHKTAGRINKSQTRRLT

ATG9

Autophagy-related protein 9

866 amino acids

Required for autophagy that plays an essential role in plant nutrient recycling (PubMed:12114572). Contributes to efficient autophagic flux, especially in early autophagic process prior to the fusion of the autophagosome with the vacuole (PubMed:24805779).

Belongs to the ATG9 family.

99.467 kDa

MMSSGHKGPNVRNFFKWQRGESSSSLTTGLLHNESHEIELSNYGGIPSPGSESPSGLLNGESLNVQPIADLDLFVERLYSYYRDKGLWCIIVKWAVELLSLGFIICFSGFFLLYVDWNGLQNAKCGMDAVESGTKPCDLVKEAIHPHPLSPFTLTTAIIVGYLALFSVYWLFCFLRFFAQLKDTLDFRHFYYNNLHVTDNEILTMPWATVLEKVVQLQSSQCLCVVKDLSAHDMVMRLMRKENYLIGMLNKGLLSFPISHWIPGAGPAVKSAPDGTQYHLVLTKTLEWTLNWCILQSMFDCNFRVRRDFVSNPTTLKKRLFVVGLAMLLLSPFLVIFMLVYLFLRHAEQFYNHPSTASSRRWSNLSKWLFREFNEVDHLFKHRINSSVVHASEYLKQFPSPIISIIAKFVSFVSGGFAAVLIIIAFLEESLLEGHIFGRNLFWYAAVFGTITAISRAAISDELLVLDPVGTMSLVVQNTHYMPKRWRGKENKDDVRLELETLFQYTGMMLLEEIASIFITPFLLMFVVPKRVDDILQFIKDFTVDIEGVGHVCSFSAFYFENHGNIKYGSPHNATRREQRSSQGKMEKSFLSFQSSYPSWESDSLGKQFLSNLRTFRDRKLHEINTRHSSPSRAWRESTNTPALYRDIPRNPLASGNHTDSMWLIDPDQRNHPYLLDWYYTSQAHNRTDHPIERANEILTANQNATDCWPPDLGIRGEDSRDLLNMEASTSGQFFRESILRHDQPEGEDSYGSQHPLDGRNQWWGRGNHSQISTAHPATTNSFIEPPDFINRYTAGNLLDNSWSRRSIEEEDEEEEELDWEENARRNLSRTTFMDDNDIEAGIDLHFDDVYSSRPQETSTSSTTLR

atg9

Autophagy-related protein 9

820 amino acids

Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Required for mitophagy. Cycles between the PAS and the cytoplasmic vesicle pool and may participate in supplying membrane for the growing autophagosome. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. Different machineries are required for anterograde trafficking to the PAS during either the Cvt pathway or bulk autophagy and for retrograde trafficking.

Belongs to the ATG9 family.

92.456 kDa

MMASNVLSRLLPQTGQSVYETIRQHDNDSDASDVEERAGLVYDDDVNLGNRFSDRELEEAMADATREGSSSPSDTFLTPQIAQRGERSASSGPRMRKPNNPRFMRSVTPRPEFVEDDLDDDHDDDVPASLLMEGQHDDEYLRTRLPPPPSHHFSDPQPSRSARSPRREHIRTFAFVVGFTTFLTNCIDYRLVRTSKSLDQILISKCTSRMSASSTFLLWLLCLFWIGKIFQLILDIRRLKNMHDFYHYLLGVSDAEIQTISWQEVVSRLMTLRDANPATAGAVSAFNRRLLGSQSKQRMDAHDIANRLMRKENYLIALINKDILDLTLPIPFLRNRQLFSRILEWNINLCIMDYVFNEQGQLSSRQYTPLAEWKFREFNELWHLFEKRINLSYPYATRYVDQFPKDKTVQVAGFVAFISGALASVLALASILDPELFLGFELTHDRTTLFYLGVFGSVWAFARGMVPEETLVFDPEYALLEVIQFTHYFPSHWKGKLHSDDVRREFAVLYQMKIIIFMEEILSMIFTPFILWFSLPKCSERVIDFFREFTVHVDGMGYLCSFAVFDFKKGTNVIPQGHINQRDARQDPRVDYFSTKDGKMLASYYGFLDNYGGNPRATNANKRAFHPPPTFPSLGSPPFVGASNIGNRQDPIQARVNTASAALGQQSMLGATRLGALGVGDTQSPAPSLLLDPQHQPSASGFRATNHIAPHHRQRLGRPPPAPVSESIIDDNEPSIAAARRPAPRRKSGQLHTNSGSSEALGAGDSNVEDSWGMKSGGEVNDEDAEENVDDVVGGAGVLGLIQQFQKVNKDNRPRAAVGL

ATG9

Autophagy-related protein 9

808 amino acids

Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Required for mitophagy. Cycles between the PAS and the cytoplasmic vesicle pool and may participate in supplying membrane for the growing autophagosome. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. Different machineries are required for anterograde trafficking to the PAS during either the Cvt pathway or bulk autophagy and for retrograde trafficking.

Belongs to the ATG9 family.

93.175 kDa

MPDVHLSSSFAEGNTSEQNENDTFLSRIFGFHSIYNQLDNYQYYDPESQVGDSMIRRDGGSNHLLDSESDSDLSSIESSSSSQDQPPSIHANDIQMQPYEPPTQPYGEIDPQPQNAPIMTESAPSHGILNNGAVSTDEAQVQFRKTKTLPSFHTMYQRQARGRVFIPSRERALYLWANIVNMDEFLSDLYYYYRGRGVMNIVLGRIVDLATLVFVIGFASFLAWGVDYDKFLSRGQKSLTLSDLIIPHYISKAPAMAKLLLFGFAIYITLRIVQLYFDFRYKLSEIRNFYRQLLDIPHDDELMTISWATIVERLMELKDFNTLTSSSHYVNDLKSKVRLNAHDIANRIMRKENYIIALINKDTLNLGFEIPLLSVLNPILNTRAVLTRTLEWNLKLCIYNFVFNNQGQVNPNVLKDYNRNMLAKELSSRFKMAAIINLLLCPFIVVYFVLLYFFRYFNEYKTNPSSLIGLRQYTPWAEWKLREFNELPHFFVKRLQLSIGPANTYINQFPRGFLVVNIMTLVNFVAGAITAVLVVMGLWFEDEEHSFWAFELTENKSALFYISIFGTIWAVTAGSLATDTSSTESANSSSPFYYDPEASLRYVTQFTHYMPSTWSKKLHTAEVKGEFCELFSLKIVVIINELLSLVLTPFILWFKLSSQSGAIIDFVREYSVYVDGLGYVCYFAMFNFEKKDKNMMHDLNKKKKKSPSHRTKRDDIEEEEESDNGVPNGDDKMIKSYMYFLESYDDRERAARPTPKSRQLPRTRLPPGSISESTYNVDHILEEEELPQGKSAGVFGMINQFYKQDLGR

ATG9

Autophagy-related protein 9

788 amino acids

Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Required for mitophagy. Cycles between the PAS and the cytoplasmic vesicle pool and may participate in supplying membrane for the growing autophagosome. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. Different machineries are required for anterograde trafficking to the PAS during either the Cvt pathway or bulk autophagy and for retrograde trafficking.

Belongs to the ATG9 family.

88.023 kDa

MDRDSPFADPDRSDPLPAPSNTLKASIFAQSRIVHPSTSVYNQFGRHRHDDIGQESFHEGIQPSVASLANLQGSYTAKSIHPHHSAIGLRNSSYDDHGDDADEQDPEDLLSDEELGLIAGDARNPSASLSYASNRSRKRRTNPSDPRSRASAVGGLSAKQKALWMWANVDNLDAFLQEVYAYYVGRGAICIALSRSLNLLTVAFVICFSTFLFGCIDYSSIRHDGQLSDVIVGHCVAGFSPFATLVVVLLLAAFGWQAVQFVLGLSRLRAMHRFYEQLLGIPDADVQSIPWHEVVNRLSALRDQHPTTSLSSADEMELGQRTSSSLRRSHPQPLDAHDVANRIMRQENYLIALFNENILDLSVPGLRSRSPSLTRSLEWNLHFCLLGFLFDSNGQVRHAFLSERYRADLIEGLRRRFLFMAVVNAIFAPFIVLYLLLYSFFRYFEEYHKDPSNLGSRQYTQYARWKFREFNELPHLFRRRCRTSYVAASKYMDQFPKEKTAIVARFVAFVAGSFTAVLLLASVMDPDVFVHFNITPQRNVLFYIGVFGAILAVARGMIPDEHVVFEPEAMLREVIEQTHYLPQDWKGRFHSAQVHQAFGQLYTLKIYIFLQELLSVVTTPFVLWLSLPACAPDLIDFLRKYTVHVDGLGHVCSFAVFDFARQPTASTMGGAAAKGIHRQQQQQQQQQQQSGGSGRTRAPRNGMSQAKMEQSILGFRANHPDWDPAAHASTASIQRVDDDAGATTLQYGHGDGRSTSDAPTGVGAGAKVKDLIDHIYRGSGGAAGASRW

ATG9

Autophagy-related protein 9

788 amino acids

Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Required for mitophagy. Cycles between the PAS and the cytoplasmic vesicle pool and may participate in supplying membrane for the growing autophagosome. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. Different machineries are required for anterograde trafficking to the PAS during either the Cvt pathway or bulk autophagy and for retrograde trafficking.

Belongs to the ATG9 family.

89.85 kDa

MTDKSTFLSVLFGGGSVYQDLDGDGEVEDAEILRRVEEEHAQTSDNSNSDNDSGNDSDVPTSLMVEGVQDPKPGSKRRQPHRMATLSNLQSSAGPGARSVSFAQGTKTQTPIRLTKPTGVANGGLPRHKQDLGASIRTMVDPKELALWKWANVQNLDNFFAEAYMYYTGKGLVSIILSRVLNMSTIMFVVVFSTYLGSCIDYSKIKGSRTLDEVHVKQCYAKLGSFHVFVLWTFFVLWFMKLFQYVKDIRRLVDMKSFYQELLEIDENELQTISWPQVAKRMATLSEANAATQVGNSTKQRIEPHDIANRVMRKENYLVAMFHKRVLNMTVPLPQPLQRIFGRPQLLSRALEWNLSLCILDYVFNPAGQVRPMFLKSTHKQILSTGLRRRFVFAAIMNVVFAPFIILYLALLYFFRYFNEYHKNPASIGTRRYNPLAEWKLREYNELPHQFERRLTLSYIPASKYLDQFPKEKTALVSKFVSFIAGSFAAVLGIASLIDPELFLMFEISANRTVLFYIGVFGSILAVSRSLIPEETLVFDPEISLRYVAEFTHYLPPEWEGKLHTEQVKNEFSLMYEMRLIILLKELASIFLAPFILYYSLTQSCDDIVDFIRDHSVHVDGLGYVCTFAMFDFKQKSPDHQPDEDQKMLKSYLYFMDHYGDKPTNVSQTQQNVPMYSSVRLKNDGLDLNNSIMQKFQKHNGHHALSGLTQRDVGLSPAAPTATTATSGTATGAAPRRDLINFDVDESFIDQTTSNRDMDNDEQPKDKERVVDMLNQFYKKTDNMNLGA

ATG9

Autophagy-related protein 9

751 amino acids

Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Required for mitophagy. Cycles between the PAS and the cytoplasmic vesicle pool and may participate in supplying membrane for the growing autophagosome. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. Different machineries are required for anterograde trafficking to the PAS during either the Cvt pathway or bulk autophagy and for retrograde trafficking.

Belongs to the ATG9 family.

84.191 kDa

MRKLCGNGSTSMISTDSYKNTTFFVIAFSTFLISCIDYTKLFSSLSTPEAVGRLEDVLIGQCITKGSFAHTLFLIILSAFFIFQVANFAMSVPRLLDMYRFYTHLLGVPDADIQTLPWPEIVRLIGDIRKHNPVTSLSNGQATALADMVGNDAKAPVKKLDAHDIANRILRQENYLIALFNKDLLDLRVRIPVPHIFTAFIPSSMLILSADPPLPSLQSEPERKFLSFGANHLTKALEWNLRFCLLGYLFDRRGQVRKEFVREKRRKDLVQGLRRRFVFMGILNAIFAPFIILYLLIYSFFRYFEEYHKNPSSIGSRQYTPYAQWKFREFNELPHLFERRLDRSYETAKEYVDQFPKERTALVMRFVAFVAGSFAAVLLVASLIDPDLFLHFEITPHRTVLFYLGVFGSVLAISRGMVPQENMVFDPEASLNEVVRWTHYLPVEWRGQLHSQMVHQEFSKLFALKIMIFFSELLSVILTPFILFFSLPPCAAAIIDFFREFTVHVDGVGYVCSFAVFDFARHGNIDSNRPETGVQGATGPDAGDSGGGGGGGGGGFAAGKSGRQTTRRAASASPSRFKQKDWRSNENKMEQSFLHFKATHPDWQPSDPSSSLFLDRLMGAGARNRPAGGISGSIYGGGGGGGGGGGRGLGIDGSVMAEMEEERLRAKSQSYERAWAKSSHLHRPDISNPLRHPHSAASEIIEEEEGGEGDKGDDSIDGWSKRMKTDGESDDEQEEHGRLWKDDGVQIDIKQ

atg9

Autophagy-related protein 9

702 amino acids

Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Required for mitophagy. Cycles between the PAS and the cytoplasmic vesicle pool and may participate in supplying membrane for the growing autophagosome. Also involved in endoplasmic reticulum-specific autophagic process and is essential for the survival of cells subjected to severe ER stress. Different machineries are required for anterograde trafficking to the PAS during either the Cvt pathway or bulk autophagy and for retrograde trafficking (By similarity). Has a role in meiosis and sporulation.

Belongs to the ATG9 family.

81.705 kDa

MFYQPAQNKKQYDDLADIEAQNNVPNTQEVLEAWQESLDSDEDESSPLEESNGFTISEHDDFVKSVPRKNNPTDLLYSGKLLDSDEPPSVHGNSSKVPSKHPSPSFPETTSLRNLQNGSKQKPALPNFNDPHFYNEDVTRSGHPNRSIYTQLPRNEFSNARVLWNRLSARDRVLWRWANVENLDSFLQQVYTYYTGKGLSCIIVHRLFQILTVSFVIGFTTFITSCIDWPAVTPHGSLAGVTKSQCIAQMSPITYLVLWLFLSFLLALWIYYLTDIPRLWQMREFYIHALKIATADMPTVSWQRVLYRLLKLKNVNALTAEDGRVVSLHNMKRLDAYAIANRIMRKDNYFIALINNGIINIELPLLHRRILTHTTEWNINWCIFNFVFDEQGQLRSAFRNPNSRKRLSEELRRRFIVAGFLNCLFAPIVAIYLVIHNFFRYFNEYHKNPGALSTRRYTPLALWTFREYNELQHFFDERINDSYAAASHYVSQFPDFNMIRLFKYISFILGSFTAILVIITVFDPELMVTFEITKDRSVLFYLGLFGSLIAVSRSIIPDETLVFAPEKALRRVITFTHYMPGWWSDNMHSKAVQQEFCSLYSYRIVNLLWEILGILLTPVLLFFTFPSCSQDIVDFFREHTINVEGVGYVCSYAVFQDNPPYESVASLVQSRKISPLIQNKPELSRISFYEQFNTEAPRRDLR

atg9

Autophagy-related protein 9

699 amino acids

Involved in autophagy vesicles formation. May recruit atg8 to the pre-autophagosomal structure (By similarity). Required for lipopolysaccharide (LPS)-enhanced bacterial clearance through the autophagic pathway.

Belongs to the ATG9 family.

81.314 kDa

MSHEDRGGDYYPMMDDPEDRNFIQAKYPNSTGHMSSGGGSNHMSFDDNHGIEMLRDDEHSLLHESPVSIPAIHNLDSFLTDVYNYFRGKGFMCIFFNDLFELVSSLFVVLFFTFLVCFVDYSKLFSEQMPPPALRESVNFSAPIPIWLMVFLVIFSLYWLSKLFSFFSSIKTNWEISSFYKNTLKINEDDIQTIEWREVVSKIVLVPRLCIVKENMNALDIANRIMRKENYIIGLINQRILNLSIPFPFLRNLTFITKTLEWSLMYSLFNYIFDENGIIKSEFQDPTQRKRLSRGLSRRFMTIGILGLFTTPFIFFFLLINFFFEYAEELKNRPGSLFSREWSPLARWEFRELNELPHYFQNRLNLSYSHANQYVESFPSQMLSTIAKFISFLFGSVLAVFIVLGIVSDHFIMNYQIFDRTPIWYIGILGTIVAITRSLIVDENQVFQPAKHMARTVQNTHYLPMSWVGKTHTHKVRDEFLVLFEYRIVDFVRDIFSVLFTPFILIFSLPKSSQAIIDFFGNNTVVLEGVGPICQLGDFSNIRKLGDNSFGSLNHSQNKISLTNNAKLEKSIINFKCLNPEWNTDNNELLQNLNEFSKIKNNNNNNNNNGSNNHIGNHSQLPTTSVDDFQFIHDSHYIPHEIIDAVLGTHHHSQQSNNNAPRFKTGRVDQNILNAVNDLHQSFYESQYKHKNDNFVNSI