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AC2

Gene
AC2
Protein
Transcriptional activator protein
Organism
Bean golden yellow mosaic virus (isolate Puerto Rico-Japan)
Length
172 amino acids
Function
Strong activator of the late viral genes promoters. Enhances the expression of the capsid protein and nuclear shuttle protein. Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs. Suppresses the host RNA silencing by inhibiting adenosine kinase 2 (ADK2), a kinase involved in a general methylation pathway. Also suppresses the host basal defense by interacting with and inhibiting SNF1 kinase, a key regulator of cell metabolism implicated in innate antiviral defense. Determines pathogenicity (By similarity).
Similarity
Belongs to the geminiviridae transcriptional activator protein family.
Mass
19.551 kDa
Sequence
MESRFKLKEEYHQSCCAIQVRVPVIKTSSTKRKTELYTTGPFIMRSSSPSQPPSIKAQHRIAKHKAIRRRRIDLNCGCSIFYHIKCADHGFTHRGEHHCASGREFRFYLGGTKSPLFQDHAGGRSSIHTDKDIPHPSQVQSQPQESTGSPQSIPELPSLDDIDSSFWDDIFK

Gene
AC2
Protein
Transcriptional activator protein
Organism
Bean golden yellow mosaic virus (isolate Puerto Rico)
Length
172 amino acids
Function
Strong activator of the late viral genes promoters. Enhances the expression of the capsid protein and nuclear shuttle protein. Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs. Suppresses the host RNA silencing by inhibiting adenosine kinase 2 (ADK2), a kinase involved in a general methylation pathway. Also suppresses the host basal defense by interacting with and inhibiting SNF1 kinase, a key regulator of cell metabolism implicated in innate antiviral defense. Determines pathogenicity (By similarity).
Similarity
Belongs to the geminiviridae transcriptional activator protein family.
Mass
19.59 kDa
Sequence
MESRFKLKEEYHQSCCAIQVRVPVIKTSSTKRKNQLYTTGPFIMRSSSPSQPPSIKAQHRIAKHKAIRRRRIDLNCGCSIFYHIKCADHGFTHRGEHHCASGREFRFYLGGTKSPLFQDHAGGRSSIHTDKDIPHPNQVQSQPQESTGSPQSIPELPSLDDIDSSFWDDIFK

Gene
AC2
Protein
Transcriptional activator protein
Organism
Pepper huasteco yellow vein virus
Length
138 amino acids
Function
Strong activator of the late viral genes promoters. Enhances the expression of the capsid protein and nuclear shuttle protein. Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs. Suppresses the host RNA silencing by inhibiting adenosine kinase 2 (ADK2), a kinase involved in a general methylation pathway. Also suppresses the host basal defense by interacting with and inhibiting SNF1 kinase, a key regulator of cell metabolism implicated in innate antiviral defense. Determines pathogenicity (By similarity).
Similarity
Belongs to the geminiviridae transcriptional activator protein family.
Mass
15.343 kDa
Sequence
MTGSKKTPSTSPSKKLSSPPEVKLRHRFAKRQIRRRRIDLACGCSIYIHINCVNNGFTHRGTHHCSSSSEWRFYLGASKSPIFQNTASGDANVHTQPGISHSSQSKPQHEDSVGSPQSLLQLPSLDDVDDDFWADLLK

Gene
AC2
Protein
Transcriptional activator protein
Organism
African cassava mosaic virus (isolate West Kenyan 844)
Length
135 amino acids
Function
Strong activator of the late viral genes promoters. Enhances the expression of the capsid protein and nuclear shuttle protein. Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs. Suppresses the host RNA silencing by inhibiting adenosine kinase 2 (ADK2), a kinase involved in a general methylation pathway. Also suppresses the host basal defense by interacting with and inhibiting SNF1 kinase, a key regulator of cell metabolism implicated in innate antiviral defense. Determines pathogenicity (By similarity).
Similarity
Belongs to the geminiviridae transcriptional activator protein family.
Mass
15.159 kDa
Sequence
MQSSSPSQNHSTQVPIKVTHRQVKKRAIRRRRVDLVCGCSYYLHINCFNHGFTHRGSHHCSSSNEWRVYLGNKQSPVFHNHQAPTTTIPAEPGHHNSPGSIQSQPEEGAGDSQMFSQLPDLDNLTASDWSFLKGL

Gene
AC2
Protein
Transcriptional activator protein
Organism
African cassava mosaic virus (isolate Nigerian)
Length
135 amino acids
Function
Strong activator of the late viral genes promoters. Enhances the expression of the capsid protein and nuclear shuttle protein. Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs. Suppresses the host RNA silencing by inhibiting adenosine kinase 2 (ADK2), a kinase involved in a general methylation pathway. Also suppresses the host basal defense by interacting with and inhibiting SNF1 kinase, a key regulator of cell metabolism implicated in innate antiviral defense. Determines pathogenicity (By similarity).
Similarity
Belongs to the geminiviridae transcriptional activator protein family.
Mass
15.178 kDa
Sequence
MQSSSPSPNHSTQVPIKVSHRQFKKRAIRRRRVDLVCGCSYYLHINCSNHGFTHRGTHHCSSSNEWRVYLGNKQSPVFHNHQAPTTTIPAEPGHHNSPGSIQSQPEEGAGDSQMFSQLQDLDDLTASDWSFLKSL

Gene
AC2
Protein
Transcriptional activator protein
Organism
Indian cassava mosaic virus
Length
135 amino acids
Function
Strong activator of the late viral genes promoters. Enhances the expression of the capsid protein and nuclear shuttle protein. Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs. Suppresses the host RNA silencing by inhibiting adenosine kinase 2 (ADK2), a kinase involved in a general methylation pathway. Also suppresses the host basal defense by interacting with and inhibiting SNF1 kinase, a key regulator of cell metabolism implicated in innate antiviral defense. Determines pathogenicity (By similarity).
Similarity
Belongs to the geminiviridae transcriptional activator protein family.
Mass
15.349 kDa
Sequence
MRPSSPSKDHYTQVPIKVQHRAAKRKRIRRKRVDLNCGCSYYVHINCHNHGFTHRGTHHCSSGDEWRLYLGGTKSPLFQDHSTRQQTVRNEPGHNNRPDTVQPQPEESVGTTSMLDGFQGLDDLTASDLAFLEGI

Gene
AC2
Protein
Transcriptional activator protein
Organism
Mungbean yellow mosaic virus (strain Vigna)
Length
135 amino acids
Function
Strong activator of the late viral genes promoters. Enhances the expression of the capsid protein and nuclear shuttle protein. Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs. Suppresses the host RNA silencing by inhibiting adenosine kinase 2 (ADK2), a kinase involved in a general methylation pathway. Also suppresses the host basal defense by interacting with and inhibiting SNF1 kinase, a key regulator of cell metabolism implicated in innate antiviral defense. Determines pathogenicity (By similarity).
Similarity
Belongs to the geminiviridae transcriptional activator protein family.
Mass
15.219 kDa
Sequence
MRNSTPSKNHFSPPSIKAQHKVAKKRAIRRSRIDLSCGCSYYIHINCRNYGFSHRGQHHCSSTQEWRLYLGGAKSPLFQDHAAPSNSSRVPDVCDPNTDNVQPRVEESTADAQMLPGSDALPLFDGDFWDDIIDF

Gene
AC2
Protein
Transcriptional activator protein
Organism
Squash leaf curl virus
Length
131 amino acids
Function
Strong activator of the late viral genes promoters. Enhances the expression of the capsid protein and nuclear shuttle protein. Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs. Suppresses the host RNA silencing by inhibiting adenosine kinase 2 (ADK2), a kinase involved in a general methylation pathway. Also suppresses the host basal defense by interacting with and inhibiting SNF1 kinase, a key regulator of cell metabolism implicated in innate antiviral defense. Determines pathogenicity (By similarity).
Similarity
Belongs to the geminiviridae transcriptional activator protein family.
Mass
14.584 kDa
Sequence
MPNSSSSKVPSIKAQHRIAKKRAVRRRRIDLDCGCSIYIHINCAKDGNGFTHMGRHHCASGREFRFYLGGSKSPLFQDVQXGGSTLHAHKDIPHTNPVQPQPEESTKSSQSVPELPSLDGIDSSFWDDIFE

Gene
AC2
Protein
Transcriptional activator protein
Organism
Abutilon mosaic virus (isolate West India)
Length
129 amino acids
Function
Strong activator of the late viral genes promoters. Enhances the expression of the capsid protein and nuclear shuttle protein. Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs. Suppresses the host RNA silencing by inhibiting adenosine kinase 2 (ADK2), a kinase involved in a general methylation pathway. Also suppresses the host basal defense by interacting with and inhibiting SNF1 kinase, a key regulator of cell metabolism implicated in innate antiviral defense. Determines pathogenicity (By similarity).
Similarity
Belongs to the geminiviridae transcriptional activator protein family.
Mass
14.627 kDa
Sequence
MRSSSPSQPPSIKKAHRQAKRRAIRRRRIDLQCGCSIYFHIDCTGHGFTHRGIHHCTSGGEWRVYLGDSKSPVFQDIQSRGPAIHQNEDIPCTNTVQPQPEESVASPQSLPELPSLDDFDDSFWVNLFK

Gene
AC2
Protein
Transcriptional activator protein
Organism
Cabbage leaf curl virus (isolate Jamaica)
Length
129 amino acids
Function
Strong activator of the late viral genes promoters. Enhances the expression of the capsid protein and nuclear shuttle protein. Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs. Suppresses the host RNA silencing by inhibiting adenosine kinase 2 (ADK2), a kinase involved in a general methylation pathway. Also suppresses the host basal defense by interacting with and inhibiting SNF1 kinase, a key regulator of cell metabolism implicated in innate antiviral defense. Determines pathogenicity (By similarity).
Similarity
Belongs to the geminiviridae transcriptional activator protein family.
Mass
14.634 kDa
Sequence
MQNSSLLKPPSIKAQHKIAKRRAVRRRRIDLNCGCSIFLHINCADNGFTHRGEHHCSSGREFRFYLGGSKSPIFQDTTRRGPVVHQNQDLPHPSPVQPQPTESIGSPQSLLQLPSLDDFDESFWADIFK

Gene
AC2
Protein
Transcriptional activator protein
Organism
Tomato golden mosaic virus (strain Yellow vein)
Length
129 amino acids
Function
Strong activator of the late viral genes promoters. Enhances the expression of the capsid protein and nuclear shuttle protein. Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs. Suppresses the host RNA silencing by inhibiting adenosine kinase (ADK), a kinase involved in a general methylation pathway. Also suppresses the host basal defense by interacting with and inhibiting SNF1 kinase, a key regulator of cell metabolism implicated in innate antiviral defense. Determines pathogenicity.
Similarity
Belongs to the geminiviridae transcriptional activator protein family.
Mass
14.888 kDa
Sequence
MRNSSSSTPPSIKAQHRAAKRRAIRRRRIDLNCGCSIYIHIDCRNNGFTHRGTYHCASSREWRLYLGDNKSPLFQDNQRRGSPLHQHQDIPLTNQVQPQPEESIGSPQGISQLPSMDDIDDSFWENLFK

Gene
AC2
Protein
Transcriptional activator protein
Organism
Tomato mottle virus (isolate Florida)
Length
129 amino acids
Function
Strong activator of the late viral genes promoters. Enhances the expression of the capsid protein and nuclear shuttle protein. Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs. Suppresses the host RNA silencing by inhibiting adenosine kinase 2 (ADK2), a kinase involved in a general methylation pathway. Also suppresses the host basal defense by interacting with and inhibiting SNF1 kinase, a key regulator of cell metabolism implicated in innate antiviral defense. Determines pathogenicity (By similarity).
Similarity
Belongs to the geminiviridae transcriptional activator protein family.
Mass
14.503 kDa
Sequence
MRSSSPSQPPSIKRAHRQAKKRAIRRRRVDLQCGCSIYFHLGCAGHGFTHRGTHHCTSGGEWRVYLGARKSPLFQDTQSRGPTVYQNEGIPRTDTVQPQPEESVASPQSLPELPSLDDVDDSFWINLFS

Gene
AC2
Protein
Transcriptional activator protein
Organism
Potato yellow mosaic virus (isolate Venezuela)
Length
129 amino acids
Function
Strong activator of the late viral genes promoters. Enhances the expression of the capsid protein and nuclear shuttle protein. Acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs. Suppresses the host RNA silencing by inhibiting adenosine kinase 2 (ADK2), a kinase involved in a general methylation pathway. Also suppresses the host basal defense by interacting with and inhibiting SNF1 kinase, a key regulator of cell metabolism implicated in innate antiviral defense. Determines pathogenicity (By similarity).
Similarity
Belongs to the geminiviridae transcriptional activator protein family.
Mass
14.736 kDa
Sequence
MRSSSPSQPPSIKKAHRQAKKRAIRRRRIDLDCGCSIYFHIDCAGHGFTHRGAHHCTSGREWRVYLGDRKSPLFQDKPSRGHAIHQDQDIQRPNPVQPQPQESIGSPQSIPELPSLDDIDDSFWVELFS