Zinc phosphodiesterase, which displays tRNA 3'-processing endonuclease activity. Involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA. Can process the mitochondrial tRNA-like structures (t-elements).

Belongs to the RNase Z family.

942 amino acids

MLTSSMPQNLSLFGFSPLKSSSFALILRPFSLYPPIFASSSPAPSRRPPRTAGYRRSGPSPPRRKWSSFEEQKRKGRSPMEKDKAISFNHSSDSFEFNKRRAEGLDKVDKPKKNLKRNTRTLNPTNTIAYVQILGTGMDTQDTSPSVLLFFDKQRFIFNAGEGLQRFCTEHKIKLSKVDHIFLSRVCSETAGGLPGLLLTLAGIGEQGLSVNVWGPSDLKYLVDAMRSFIPRAAMVHTRSFGPSLNISDSAPQIGLSKPKDDAYVLVDDEVVKISAILLEPSRLEESGSKPGETAVIYVCELPEIKGKFDPKKAMALGLRAGPKYSYLQSGQSVKSDFKDITVHPSDVMGPSVPGPVVLLVDCPTESHAEELLSIPSMKTYYSCLDNSTDGAKLVNCIIHLSPASVTNSSTYRSWMKRFHSAQHILAGHEAKNMEFPILRASSRITARLNYLCPQFFPAPGFWSHQHDNNSINPTSLSKCFDSNLGESISAENLLKFTLRPHGNLGVDRSSIPSRLTALRVMDELLSEIPEISSKTEEIKQLWNGQHNKMMIEEPWLGESTVPSCLENIRRDDMEIVLLGTGSSQPSKYRNVTAIYIDLFSRGSILLDCGEGTLGQLKRRYGLEGADEAVRNLRCIWISHIHADHHTGLARILARRRELLKGLAHEPAIVVGPRSLKNFLDAYQRLEDLDMEFLDCRNTTTTSWASVETSRPEKNTSSGNAEGSLFSKGSLMQSIYKRPSSPLTDNSSALPFLKKLKKVLGEMGLEHLISFPVVHCPQAFGVSLKAAERKNIAGDEIPGWKMVYSGDTRPCPEMVEASKGATVLIHEATFEDALVEEAVAKNHSTTKEAIKVGSSAGVYRTVLTHFSQRYPKIPVIDESHMHNTCIAFDMMSINMADLHVLPKILPYFKTLFRNQVVEEEEEEEETDDDSLIRDKVPSFFIN

104.7 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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