Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit.

Belongs to the WD repeat TRM82 family.

502 amino acids

MVVNYQHPIQCIRYVEKQTAGFRNLFLASAGSKIYTYAAETGRKLAIWPEAPNASHSTVVSVAPSSEGDEPSAKKRKVSPVPEQTAKGGQPEASTAWSTIPILTVSSDGNFLVAVTGEDKCLRVFEIEESGHLKQLSERHMPKRPSAITLVDDDKTILCGDKFGDVYSLPLIDTGKSSIAPKIHAKMKPNQPAATTLTVHSKRNLASLEQQLRHYSQNEKTAEEKPTSAFELHLILGHVSMLTDLVYVSVPVDATSGRQRPYIFTADRDEHIRVSRGPPQAHIIENYCLGHTSFVSSLCVPQWAPEYLVSGGGDNHLIVWRWNESRLVQKVPLLEEGTDSEVVVRRIWALSLTKAANSQENANVILVALDGSSKLLCFTLESDGSLKAQNSIQASGNVLDLTVPSENSSIVVSVDAVREAGSTQEWRTSPSSPSTLVEAFRLKPASEGPLDWERTSEAITAQINSEGTSDISADLDEKQKKELNDSLYSLGNLRKKNMGEDD

54.9 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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