Required for the proteolytic cleavage of the transcription factor pacc-1 in response to alkaline ambient pH. May act as a scaffold protein that recruits the calpain-like protease palB/cpr-8 via snf7/vps-3 to its substrate pacc-1 (By similarity).

Belongs to the palA/RIM20 family.

854 amino acids

MTTTHVLSLPFRKSTQLSLSRAIQQYISAKYDQHPDMFRHDLDTIDALRRDAINVREAHPSGIRKLQMYAAQLVWIGGKFPIDVGADFTWYPALGYHTEHPLVQNNLKYELMNVLYNLAALYSQLAVASNRNSTEGLKTAASWFSHSAGVLTHIKTQVLPELRMPSPPDDMDETTLESLIQLFLAEAQECYWQKAVMDGYKDASIAKLAARVSDLYNEAGEAAMRSEAISSAWIHHMSAKHHHFAAAAQFRAASDCLERKKYGEEIARLRDAVACVNEGLKETRGGYLSKAVVEDLQGLKRRLEEDLKRAEIDNDRVYLHIVPPKTELKRLDRANMAVARVPPQVAKPYEFLGDPSAEFGPALFTKLVPFAVHVAVSIYEERRDRLVNNSIISELESMTSQLHEILSSLNLPGSLQALEKPLGLPGTLVQHADEIRQADALYRLQQGLTDIDKLCSSDLAIFEEGRSLLLAEEEEDSRLRLKYGTERWNRPQSRQDPSPNGGTKLWRQAQDIEGYFGSSTASDQVVREKFNAVRDTLTILAGSDRSIMDFIPNSRRTDIPESLKPALGRLRSAYNDVQRLESRRRKRVESLRARSRADDIKPDILVEAARLERAYPTTAIATAHFEDFFEKRLDRLYESELEAVERDKQEQEKIVQEVKRANKEFEAQKRQVDRAGGGNREREEALQKLDAAYYKYKEIVSNVEVGRKFYNDLSQIVEQWRGLVRGWVSERRRDARSLEEEINMPPLSSLNMHQSSFSYQQQQHHQQPPPPPPQIPFPEPIQPHQPIVEQAHIQSWADNVPQQQPKPVAPGAWAPNMGIKFGSPVAQGQQHQQEQGQPGPVNATWDPSQGIRFG

96.9 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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