Required for the proteolytic cleavage of the transcription factor RIM101 in response to alkaline ambient pH. May act as a scaffold protein that recruits the calpain-like protease RIM13 via VPS32 to its substrate RIM101 (By similarity).

Belongs to the palA/RIM20 family.

631 amino acids

MSQLSAVPLKMTLQVDMQAQLAAIIDSTFYQVSSVFIDDLAAVNDMRNRSLMEADASVSNLEALLEYCKTLFALIAKFPDRQIEFTWFETLGHKAYGKTSNLWKFELFNVIYNIGAVKSLLASSMGNDELKEACRYLQESAGCFQYILSAMERELESVIDEKTIRAVLNLMLAQAQECCWARALRDAMKHSPIARLALQVSNFYEEAHRYARISPVIRTKLVKYINEKSFYFAAVAHYRHALHFEEKQQYGNAVRSLNEAQEKIKGAGWGPEVLPFEKELNDTLNTLQRDNDLIYLQHIPSQCPVINPVSMVKPILIDLLSTGTQKIHLFRNLLPIDVIESSAAFNIRQDKYVEDYVKSPLVALNKLLHNSLPENEALPGMKHLTEEEFDIYAKTLAGLNEFSSQLGERLTVIKSLIDGATTRLPAEANHHADQDNSKDIVEEYNKRIVTLQGYLRQGEEITRETTQIFETVDRDLLTTQLQLAATNNPTMRKVEALTKERYDYIAEVEKKSLQNRILPSLVSNYKETGSLDFEPIFQEHLKMFKKDIEYVQLGKKRNAELIAELNAEEGEESGKIKRLSPRDIQIQDFKHSLHLLEQVKENIEEGQVFYEDLKESIGVLHEDVTDFLNKS

72.2 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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