May play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. May remove the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP (By similarity).

Belongs to the DCP1 family.

578 amino acids

MAAAAAGGLPGKGHDISLAALRRHDPYISRIVDVASQVALYTFGHRANEWEKTGVEGTLFVYTRSASPKHGFTIMNRLSMENRTEPITKDLDFQLQNPFLLYRNGTLSIYGIWFYDKEECQRIAKLMKNLTQSEQLKACHGAGSSPVTLSSGEGQEVDILQMLTKAKDEYTKCKTCSEPKQMTNSSAICDNPKLIKPVPVRPSSSQRLQGPAPSKTSDPEPQHLSLTALFGKQDKAPCQETVKPSRTFAHHHHHHHQQQQETRPVHHGVACSLSCEEPRKLSLPVEKQLCPAIQKLMLGSPGLHPLPQHPEQWSCKSGSPSPAGGILPGPVQLGSPWNGRVAHCTQSTCRGHKLLEQLQGAPGAVHKYNPCAPTGPAVATQVAPGQSVAQSQLVYFSGPLQPPAPGHQALRKEQGALPAQAVSLSGSQESSPTVLPTQELLRKLQVVHQEQQAAPRPALAARFPVSAQGSGTEKPLEAWVSKTASMEKQAPLLQSTCAPLRETDNGLMALGGQELPAASSNLLLPLQNWESSTVASRPLTRLQLQEALLNLIQNDDNFLSIIYEAYLFSVTQAAMRTT

62.7 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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