Acts as an adapter to assemble/stabilize a Toll/wek/Myd88/tube complex; required for efficient recruitment of Myd88 to Toll. Dispensable for innate immune response; plays a minimal role, if any, in the immune defense against Gram-positive bacteria and fungi. Involved in dorsoventral axis determination.

470 amino acids

MGVPTSDWIYWCRLCARDDVVYKVRERDDDLVRIISKCFDVEMTLEEPELGSMLCEECYSVIGQLITFSDSVSKVQAIFELLRHSEPQDSQDLDALRLEYGLPPACKQDLEFLDIDDTEDRCSLVEELTISDHSTSPSPDFEAQTVRTRANLKQCNSDPKVLASPTASIPEVETKRSRRQQFAAKRNSKVYTATESDDEEAILDEDEAVSPPPLKRKRGRPKGSGKQKNVDDSDNVTSREPDDNAKSKQDDKTSELSMSPHGSQSSNFVDYPCKICNETFMSFMALRRHKHDMHGGPKKYVCDHCGKGLKTFTSLVEHQLVHTEEKPCICPVCNAGFKNKARLRVHSQTHGEPKFECNVCGKKLQTRAILNKHKYVHTDERRFKCEVCGSGCKNSTALKIHLLGHTGLRPYVCKYCGKAFASNTNCRSHKWKKHPELASKEDETESSRVPVPTLEELRAITREMAKAKQD

53.2 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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