Plays a role in the reduction of telomerase activity during differentiation of embryonic stem cells by binding to the core promoter of TERT and controlling its down-regulation.

1386 amino acids

MYPNWGRYGGSSHYPPPPVPPPPPPVALPEASPGPGYSSSTAPAAPSSSGFMSFREQHLAQLQQLQQMHQKQMQCVLQPHHLPPPPLPPPPVMPGGGYGDWQPPPPPMPPPPGPALSYQKQQQYKHQMIHHQRDGPPGLVPMELESPPESPPVPPGSYMPPSQSYMPPPQPPPSYYPPSSAQPYLPPAQPGPSKPQLPPPPSIPSGNKTAIQQEPLESGAKNKTAEQKQAAPEPDPSTMTPQEQQQYWYRQHLLSLQQRTKVHLPGHKKGLVTAKDVPEPIKEEAPGPAASQVAEPLAAEKPPLPPPNEEAPPPLSPEEPQSEDSEDSEDSEEDARFKQLKAIAAHWQAAAAHWQQQQQQRVGFQYQGIMQRHTQLQQILQQYQQVIQHSPHIQTMSLDVQLRHYEMQQQQFQHLFQDWEREFQLWEEQLHSYPHKDQLQEYEKQWKTWQGHMKATQTYLQEKVNSFQTVKSQYLGNMAMPPPFVPYSQMPPPLPTMPPPVLPPSLPPPVMPPALPTSIPPPGMPPPVMPPSLPTSVPPPGMPPSLSSGPPPVLPPPALSSAGSPPVLPPPALPGGPPILPLPPLSSATPPPGIPPPGAPQGMPPQLTAPLPPASGSQNSQIPEKPRQALLPTPVSFGSTPPSPYHPPPQSEQVNSKPLNKVFSSEQGLGESSALSQSIIAAKDTPVKSGGLLADPPKGSFLEGPRGPREQKEQLQKLKDFGSEPQMADHLPPPDSRLQNPSRPGMYPPPGSYRPPPPMGKPPGSIVRPSAPPARSSIPMTRPPVPIPPPPPPPPPPPPPPPVIKSKTSSVKQERWDEDSFFGLWDTNDDQGLNSEFKRDTATIPSAPVLPPPPVHSSIPPPGPMPMGMPPMSKPPPVQHTVDYGHGRDMPTNKVEQIPYGERITLRPDPLPERSTFDADHAGQRDRYDRDRDREPYFDRPSNITDHRDFKRDRETHRDRDRDRVLDYERDRFDRERRPRDDRNQSYRDKKDHSSSRRGGFDRPSYDRKSDRPPYEGPPMFGGERRTYPEERMPLPAPALGHQPPPVPRVEKKPESKNVDDILKPPGRESRPERIVVIMRGLPGSGKTHVAKLIRDKEVEFGGPAPRVLSLDDYFIAEVEKEEKDPDSGKKVKKKVMEYEYEADMEETYRTSMFKTFKKTLDDGFFPFIILDAINDRVRHFDQFWSAAKTKGFEVYLAEMSADNQTCGKRNIHGRKLKEINKMAEHWEVAPRHMMRLDIRSLLQDAAIEEVEMEDFDANIEDQKEEKKDAEEEESELGYIPKSKWEMDTSEAKLDKLDGLRTGTKRKRDWEAIASRMEDYLQLPDDYETRASEPGKKRVRWADLEEKKDADRKRAIGFVVGQTDWEKITDESGHLAERALNRTKYI

155.1 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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