Description
Enhances the STK11/LKB1-induced cell growth suppression activity. Negative regulator of amino acid starvation-induced autophagy.
Family
Belongs to the WD repeat WDR6 family.
Sequence
MDAHEDYVWPRATSELILLPVTGLECVGERLLAGEGPDVLVYTLDFGGHLRMMKRVQNLLGHYLIHGFRVRPEPNGDLDSEVMVAAFGSKGLRIVKISWGQGRFRELWRSGLWNMSDWIWDARWLEGNIALALGHNSVVLYDPVVGCSLQDVPCTDRCTLSSACLIGDTWKELTVVAGAVSNQLLVWYPAAALTDDKPVVPDRRVSGHVGVIFSMSYLESKGLLATASEDRSVRIWKVGDLRVPGGRVQNIGHCFGHSARVWQVKLLENYLISAGEDCVCLVWSHEGEILQAFRGHQGRGIRALAAHERQAWVITGGDDSGIRLWHLVGRGHPGSGVFALSFKSHSRPGVLKAVTLAGSWRVLAVTDAGALYLYDLEVKCWEQLLEDKRFQSYCLLEAAPGPEGFGLCALANGEGRVKVVPINTPTAAVDLTLFPGKVHSLSWALRGYEELLLLASGPGGVVACLEISAAPSGKAIFVKERCRYLLPPSKQRWHTCSAFLPPGDFLVCGDRRGSVLLYPSRPDLLKDLGVVSKVGAITSAPGAGSGEGEPSLAEWGPMSTLPSLHGKQGVTSVTCHGGYVYTTGRDGSYYQLFVRGGQLQPVLRQKPCRGMNWVAGVRMVADGNMVILGFHANEFVVWSPRSHEKLHIINCGGGHRSWAFSDTEAAMAFAYLKDGDVMLYRALGGCTRPHVILRESLHGREITCVKRVGSITLGPESGVPSFLQPDHLEPGEPVEPGSEGPGLIDIVITCSEDTTVCVLALPTATGSAHALTAVCNHISSVRAVAVWGVGTPGGPQDPQPGLTAHVVSAGGRAEMHCFTIMVTPDPSPPSRLACHVMHLSSHRLDEYWDRQRHRHRMIKVDPETRYMSLAVCELDRPGLGPLVAAACSDGAVRLFLLQDSGRRLQLLAETSHHKRCVLKVHAFTHEAPNRRRRLFLCSAATDGSLAFWDLTTMLDQDSPALEAAADLGLPFQLGSPCLTVQAHSCGVNSLHTLPTREGHLVASGSEDGSLHVFVLAVEMPELEEAVGGAELLPQLQVLEEYSVPCAHAAHVTGLKILSRSLMVSASIDQRLTFWRLGHGEPTFMNSTVYHVADVADMDCWPVSPEFGHRCALGGQGLEVYNWYD
Simulated SDS-PAGE

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service