Description
Probable effector of the planar cell polarity signaling pathway which regulates the septin cytoskeleton in both ciliogenesis and collective cell movements. Together with FUZ and WDPCP proposed to function as core component of the CPLANE (ciliogenesis and planar polarity effectors) complex involved in the recruitment of peripheral IFT-A proteins to basal bodies (By similarity).
Family
Belongs to the WD repeat fritz family.
Sequence
MSFCLTELHLWSLKSTLHIADRDIGVYQYYDKKDLPVSAAEHGNLEEKQRLAESRDYPWTLKNRRPEKLRDSLKELEELMQNSQCVLCQWKSKHICQLLFGSGVLVSLSLSGPQLEKVVIDRSLVGKLISDTISDALLTDSFIILSFLAQNKLCFIQFAKKMDSLDVNKRLEKLSALDYKISYHDIPGPATRTVDRHLAINSTQDLAVCWWPLLSDDAWPWTPIASEKDRANMLLLGFTQGGLEVLSSVRTEWNPLDVHFGTRQPYQVFTVECSFSVDQEPMADSCIYESVRNKLHCVSVTRIPLRSKAISCCKNSTEDKLIVGCEDSSVILYEAHRGVTLLAQAELMPSLISCHPSGAILLVGSNQGELQVFDIALSPINIQLLAEDCLPKETLQFNKFFDFSSSLVHMQWIAPPIVFQKPKRGEICDLLFLRFNRGPLGVLLFKLGVLRRGQLGLVDLIFQYIHCDEVYEAVSVLSSMNWDTLGQQCFISMSTIVNHLLRQRLTPEREAQLEASLGTFYAPARPLLDTTVLAYRDPVGTYARRLFHHLLRYQRFEKAFLLAVDIGARDLFMDIHYLALDMGELALAEVARRRADDIDVESVCSGVELLGPLDRRDMLNEGFAGSALTPEGGNPFPDLLPSSGSTPKHTIQQKIPNGPSNRRAIERKNEVMEETEEEEEEEEEAAACTDSSVATTWDAEGELREDHRRQDTEDVGSLRMVHFGLV
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service