Component of the autophagy machinery that controls the major intracellular degradation process by which cytoplasmic materials are packaged into autophagosomes and delivered to lysosomes for degradation. Involved in an early step of the formation of preautophagosomal structures.

Belongs to the WD repeat SVP1 family.

435 amino acids

MNLASQSVDAGAGQLLFANFNQDNTSLAVGSKSGYKFFSLSSVDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTTLAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPSGLCSLSINGENCYLAYPGSASIGEVQVFDTVNLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDSIFLSASSNTETVHIFKLETIKEKPPEEPTSWTGYFGRVIMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICALATIQKISRLLVGAADGYLYIYNFDPQEGGECTLMKQHKLDGSMEPSSEILESSSHDRQVGAQTYSATVTKTYPPPSPTRHAYADDLGAVGGASEEDEMGNLRLDEDNENPPMILQTE

47.7 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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