Mediates the uptake of glutamate into synaptic vesicles at presynaptic nerve terminals of excitatory neural cells. Required for glutamate release by retinotectal synapses and visual acuity.

Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. VGLUT subfamily.

584 amino acids

METPREPAGFSKEGLKQLAGKTLGHVYRVIEKRQKPGENIELTEDGRPAQINERKAPLCDCTCFGLPRRYIIAIMSGLGFCISFGIRCNLGVAIVSMVNNSTIHLNGKIIIKEKAKFNWDPETVGLIHGSFFWGYIVTQIPGGYISSRLAANRVFGAAILLTSTLNMFIPSAARGHYGCVIFVRILQGLVEGVTYPACHGIWSKWAPPLERSRLATTSFCGSYAGAVIAMPLAGILVQYTGWSSVFYVYGCFGIFWYMFWILVSYESPAEHPTITAEERCYIEESIGESAKLLGPADKFKTPWRKFFTSMPVYAIIVANFCRSWTFYLLLISQPAYFEEVFGFEISKVGMLSALPHLVMTIIVPIGGQLADHLRSKNILSTTTVRKIMNCGGFGMEATLLLIVGYSHSKGVAISFLVLAVGFSGFAISGFNVNHLDIAPRYASILMGISNGVGTLSGMVCPLIVGAMTKHKTREEWQYVFLIASLVHYGGVIFYGIFASGEKQPWADPELTSDEKCGFIDEDELAEETGDITQSYGALGAPAKSYGATTQLNGGWAEGWDKREEYVQDGVEEGGYGYRQGGNYS

64.1 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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