Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.

Belongs to the uroporphyrinogen decarboxylase family.

353 amino acids

MPLQNDRLLRALARQPVDRTPVWMMRQAGRYLPEYRETRGQAGSFMDLCRNAELACEVTMQPLRRYALDAAILFSDILTIPDAMDLGLYFETGEGPKFRKTVRSAEAVDALPVPDAERDLDYVMNAVRTIRHELADSVPLIGFSGSPWTLATYMIEGGSSKDFRHAKALMYGDPAAMHALLDKLARSVTDYLNAQIRAGAQIVQIFDTWGGVLSTPAYREFSLAYMARIVEGLIREHEGRHVPVILFTKQGGQWLETIADSGADAVGLDWTTELSDARARVGDRVALQGNLDPNVLFASPQAIRDEVARILASYGSGPGHVFNLGHGVSQFTDPDHVAAFIEALHELSPRYHG

39 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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