Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.

Belongs to the uroporphyrinogen decarboxylase family.

354 amino acids

MSELKNDRYLRALAKQPVDVTPVWMMRQAGRYLPEYRATRAQAGDFMSLCRNAELACEVTLQPLRRYPLDAAILFSDILTIPDAMGLGLYFETGEGPKFERPISSLSDVKKIPKLDPNDDLGYVMNAVSTIRRELKGEVPLIGFSGSPWTLATYMVEGGSSKVFGKIKKMAFAEPQTLHLLLDKLADSVIDYLNAQIKAGAQSLMVFDSWGGVLSPRDYNEFSLQYMHKIVDGLIREYDGRRVPVTLFTKNGGQWIEAIAATGCDAIGLDWTINISDAKRRVGDKVALQGNMDPSMLHGTPERIRQEVATILEDFGTGNGHVFNLGHGITPDVDPENAGVFINAVHEFSAKYHK

39.3 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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