Description
Endonuclease for the repair of UV-irradiated DNA. Involved in the excision of cyclobutane pyrimidine dimers (CPD) and 6-4 pyrimidine pyrimidones (6-4PP) which forms the UV damage repair (UVDR) pathway.
Family
Belongs to the uve1/UvsE family.
Species
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
Sequence
MPSRKSKAAALDTPQSESSTFSSTLDSSAPSPARNLRRSGRNILQPSSEKDRDHEKRSGEELAGRMMGKDANGHCLREGKEQEEGVKMAIEGLARMERRLQRATKRQKKQLEEDGIPVPSVVSRFPTAPYHHKSTNAEEREAKEPVLKTHSKDVEREAEIGVDDVVKMEPAATNIIEPEDAQDAAERGAARPPAVNSSYLPLPWKGRLGYACLNTYLRNAKPPIFSSRTCRMASIVDHRHPLQFEDEPEHHLKNKPDKSKEPQDELGHKFVQELGLANARDIVKMLCWNEKYGIRFLRLSSEMFPFASHPVHGYKLAPFASEVLAEAGRVAAELGHRLTTHPGQFTQLGSPRKEVVESAIRDLEYHDELLSLLKLPEQQNRDAVMIIHMGGQFGDKAATLERFKRNYARLSQSCKNRLVLENDDVGWTVHDLLPVCEELNIPMVLDYHHHNICFDPAHLREGTLDISDPKLQERIANTWKRKGIKQKMHYSEPCDGAVTPRDRRKHRPRVMTLPPCPPDMDLMIEAKDKEQAVFELMRTFKLPGFEKINDMVPYDRDDENRPAPPVKAPKKKKGGKRKRTTDEEAAEPEEVDTAADDVKDAPEGPKEVPEEERAMGGPYNRVYWPLGCEEWLKPKKREVKKGKVPEEVEDEGEFDG
Simulated SDS-PAGE

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service