Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.

Belongs to the MurCDEF family. MurE subfamily.

532 amino acids

MEYTKSIAECIKAIEVVNCFGNDKSLINSVEYDSRKVRAYSYDDKTGLKKGAAFFALPGIHTDGKKFINSAIENGAVCIFYEGDLNNHSCDEICFVQVNDVRKTMSKVSALLYDEPSRTLGVIGVTGTEGKSSTVSFIFQLLNLCGKKAGFFSTVEYSIDGNVIPNPEHQTTPESNVVQLRLAQMRDSGCSYAVVEASSHGLSPKTARLEDVIFDAGVFMNVTQEHLEFHGTIEQYRYDKANLFRALDKNPGKGFPIFGIVNYEDPSAPYFMEATQKNVYPFSTELKDLKKIEEYKGLFAKDIEESSSGIKFTLCDFSSRKEYGCELKLAGIFNVKNILASVLAVQRITGLDIACIIEKLPLVKPVKGRMMLIDEGQDFEVLIDYAHTPSSFMTIFPSIKERIKKSGGKVISLFGSGGERDVKKRPEQGRIAALYSDIVILADEDPRGEDSVELLEMIAAGCPEKKRGEELFIIPDRPSAIKKAFSLAGKNDAVLLLGKGHENSIIFKDRTMPYDEETTARKLLIGADCTNP

58.9 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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