Description
Tyrosine-protein kinase which is required during embryogenesis for formation of the actin cable in leading edge cells of the dorsal epidermis and for the timely progression of dorsal closure. May play a role in regulation of adherens junctions and cell adhesion through phosphorylation of the beta-catenin arm.
Family
Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.
Species
Drosophila melanogaster
Sequence
MGFSSALQSRAAHEALIVRQDAELRLMETMKRSIQMKAKCDKEYAISLTAVAQQGLKIDRADEMQGSLISKSWRSYMDELDHQAKQFKFNAEQLEVVCDKLTHLSQDKRKARKAYQEEHAKIAARLNHLTDEVVRKKSEYQKHLEGYKALRTRFEENYIKAPSRSGRKLDDVRDKYQKACRKLHLTHNEYVLSITEAIEVEKDFRNVLLPGLLEHQQSVQESFILLWRNILQEAAQYGDLTADKYKEIQKRIDTVIGSINPTEEYGEFTEKYKTSPTTPLLFQFDETLIQDIPGKLQSSTLTVDNLTVDWLRNRLQELEGAVRDCQEKQMKMIEHVNGGSPVANGSIISNGSNTSNGIQSNKDSLCRQSKDLNALRCQEKQKQKLVDMIKCALNEVGCEELPSGCDDDLTLEQNFIENGYNNEQQRSNSTSSPGLGIMNELMRRGGVLTLLRGRGRHFKRKSTPQPATPMTRSRQGRFNKLQPRSQSLGSLSVIRDGNGPSPARYEPITNHRLRQAASVHYLGEEIATSSTNPPDLTRLRRTQCSMLCLGEDEEPVVLASPAPLTQLTAAVLTNTNNNHIYADLELDKKKDTSPSPECKGEQIQPKKEQIRIEINQTAPQNSIDAHLDRIDELNRVLDDRLKRTLQPSDDVNAIESAEENHIQTRKLAKDPDSQTKRSSSSSSECRSSKDTSHSKKRSLSFSQKSISNIFSNLKEFSKSPLVRMGKNHILNEEQDAKRTQPSQHHHSSGSDCPTNSSSSSSNNNNNNKNTSSNSNHSASQSTIITSTITTTITTTTTTTPSKENSRLKFKVPKIQKKSKAIRNTFRSKLLNFQLKRSKPCKQCTKRRRIHPSKSVFDFAKEFEVEQPAGSAADEQFCNCPPAGQKPVKPSVQISGHKDHPFESSSGELDENSDRDIDNDEEEEDSASDDVLSMKDHCYCVPSLAASISLSTNRPLYEEEWFHGVLPREEVVRLLNNDGDFLVRETIRNEESQIVLSVCWNGHKHFIVQTTGEGNFRFEGPPFASIQELIMHQYHSELPVTVKSGAILRRPVCRERWELSNDDVVLLERIGRGNFGDVYKAKLKSTKLDVAVKTCRMTLPDEQKRKFLQEGRILKQYDHPNIVKLIGICVQKQPIMIVMELVLGGSLLTYLRKNSNGLTTRQQMGMCRDAAAGMRYLESKNCIHRDLAARNCLVDLEHSVKISDFGMSREEEEYIVSDGMKQIPVKWTAPEALNFGKYTSLCDVWSYGILMWEIFSKGDTPYSGMTNSRARERIDTGYRMPTPKSTPEEMYRLMLQCWAADAESRPHFDEIYNVVDALILRLDNSH
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service