Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerC binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerD specifically exchanges the bottom DNA strands.

Belongs to the 'phage' integrase family. XerD subfamily.

313 amino acids

MTQTKLSTQTTTDNNQEDNDVIIEQFLDSIWLEQGLSANTLSAYRLDLQALSQWLVTQKLNWLSVTTLDLHAFLATRLDEGYKATSAARLLSTLRRFFQYLYREKLRQDDPSALLSTPKLPKRLPKDLSEQQVENLLSAPCIDEPIELRDKAMLEVLYACGLRVSELVGLSLSDISLRQGVLRVIGKGDKERLVPLGEEAIYWLEQYLQYGRPALMQGKTDDIVFPSLRGQKMTRQTFWHRIKHYAVIAGIDSEKLSPHVLRHAFATHLLNHGADLRVVQMLLGHSDLSTTQIYTHVATERLKVLHQQHHPRG

35.8 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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