Description
Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) and of T3 into T2 (3,3'-diiodothyronine). Plays a role in providing a source of plasma T3 by deiodination of T4 in peripheral tissues such as liver and kidney.
Family
Belongs to the iodothyronine deiodinase family.
Species
Canis lupus familiaris
Sequence
MGLPRPVLWLRRLWVLLQVAVQVAVGKVFLKLFPARVKQHIVAMNGKNPHFSYDNWAPTLYSMQYFWFVLKVQWQRLEDRTEPGGLAPNCPVVRLSGQRCNIWDFMQGNRPLVLNFGSCTUPSFLFKFDQFKRLIEDFCSTADFLIIYIEEAHASDGWAFKNNVNIRTHQTLQDRLQAARLLLDRAPPCPVVVDTMRNQSSQFYAALPERLFVLQEGRILYKGKPGPWNYHPEEVRAVLEKLHS
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service