Description
T1-TrpRS has aminoacylation activity while T2-TrpRS lacks it. T1-TrpRS and T2-TrpRS possess angiostatic activity. T2-TrpRS inhibits fluid shear stress-activated responses of endothelial cells. Regulates ERK, Akt, and eNOS activation pathways that are associated with angiogenesis, cytoskeletal reorganization and shear stress-responsive gene expression (By similarity).
Family
Belongs to the class-I aminoacyl-tRNA synthetase family.
Species
Oryctolagus cuniculus
Sequence
MADVTNGERCASPQELFSSIAAQGELVKSLKARKAPKEEIDSAVKMLLSLKTSYKEAMGEDYKADCPPGNSTPDSHGDPEAVDDKEDFVDPWTVRTSSAKGIDYDKLIVQFGSSKIDKELVNRIERATGQRPHRFLRRGIFFSHRDMNQVLDAYENKKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFDVPLVVQMSDDEKYLWKDLTLEQVYGYTLENAKDIIACGFDVNKTFIFSDLDYMGMSPGFYKNVVKIQKHVTFNQVKGIFGFTDSDCIGKISFPAIQAAPSFSNSFPQIFHGQADIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKTKVNKHAFSGGRDTIEEHRQFGGNCDVDVSFMYLTFFLEDDDKLEQIRKDYSSGAMLTGELKKELIDVLQPLVAEHQARRKEVTDEMVKEFMTPRQLCFHYQ
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service