Promotes LRP6 phosphorylation by casein kinases and thereby plays a role in Wnt signaling. May be a membrane scaffold protein involved in the self-aggregation of LRP6 to further enhance its activity (By similarity).

Belongs to the TMEM198 family.

360 amino acids

MPGTMETLRFQLLPPEPDDTFWGAPCEQPLERRYQALPALVCIMCCLFGVVYCFFGYRCFKAVLFLTGLLFGSVVIFLLCYRERVLETQLSAGASAGIALGIGLLCGLVAMLVRSVGLFLVGLLLGLLLAAAALLGSAPYYQPGSVWGPLGLLLGGGLLCALLTLRWPRPLTTLATAVTGAALIATAADYFAELLLLGRYVVERLRAAPVPPLCWRSWALLALWPLLSLMGVLVQWRVTTERDSHTEVVISRQRRRVQLMRIRQQEERKEKRRKKRPPRAPPRGPRAPPRPGPPDPAYRRRPVPIKRFNGDVLSPSYIQSFRDRQTGSSLSSFMASPTDTDYEYGSRGPLTACSGPPVRV

39.8 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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