Involved in translational repression of multiple mRNAs in the distal gonad (PubMed:23264733). Recruited to the 3' untranslated region (UTR) of zif-1 by oma-1 and is required for translational repression of zif-1 (PubMed:20826530). May also be involved in translational repression of mei-1 through recruitment to the mei-1 3' UTR by oma-1 (PubMed:19786575). Required for oogenesis but not spermatogenesis, for P granule formation and for the localization of car-1 and cgh-1 to P granules (PubMed:23264733). Required for normal spindle orientation in early embryos (PubMed:19786575).

761 amino acids

MTSHLDDEGLHPMVSTLLGGGTLPTVPFKAYTRERMMELRTTKASMTRPENLSEDFNGEDGKFSPLKWLEHRWEIEGIKNRPMSKKIDSLCAGADENTGLSPQRRAFSSGCKAPTDDKGRDGEYERLGGHGKNWRNGSTGGADKFASRGNDFKPSFQKGNQLERGTRGAEWKKDTTRGAKFAPRREERLTSLSGSEKLPEWADGPTTMDDMIELRGFDEPKKVKNKKNPKEKKEKEAVKAPEPVECVGSRPSSTGLKTSEPIDDPAIAYSSSGGGALPATDQELAALLGCLDIQKTSRKIDGDDMAWAHKSEETAGGTSRLSRFFAKKNKSPELDAMLSSVGGGNDENVANPMLARLFGHSGGDNNASSSGAGDIKGGMRLEDLEKGMESKEPSKVSPLQDPSQQAQLLQHLQKFAKQQAESGQHIHHHRQPTPPNGGPQHQQHLHHPMVHPGMQIIADPSLLASFAQNPVILNAYVENQLQEAVNAAIRANNGQQLPPQLHEQLRMASMRNKAFLQSQTLTFVSLQQQHQNIQQHQQQQQHHQHKGRTPAMIPASVQRQLQKSSSNADQKKEKTSQSPPESNQETSDAHNQSDAMNQLKKLHMQQNYANMVQAMNSGVGWARGNGVVNGQQQHPQQQLPPNVQMLMAQHQQAQMQHLKMMMSRAQQQHMLMAKIAQMQQQQAQMANMQERQGPSHNQQQHQPVVPSELSQVGPIQTPLEKLLASVGVQGSQFTGSGDRIPSSVRPMSLEDLEKQLTAVPK

84 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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