IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.

Belongs to the IF-3 family.

520 amino acids

MAIWRIINRSYLKYASNQLTRNYYTQVCLASSTHVVKQTTKLSSFDIPNSDICTRPSNIFQNLRFLATSAQTRKKEAEVDSDGPRLNEKITGDYVRLVSEEGHCVVSLREALRRAKELQCDLVEVQRDAKPPVCKIVKYSLELYKKAKVGKERAKAKRAEAIRPDIKEIRFTPKIEAKDLKFKSDQALKLMESGYRVKCLAVPDKDKHKELEPEKLLELLFRFTCFIGDALVESWPEADRKGAVVIVRHAKFGPPKKGGVKLMKDIDIKSARVKEESPKPDSSKAGVATVDDQEDIEKSEPRFSVEQAQPVKFQNAYAKREPSSEFSGGRDASRFEPQSPNQHVNPQRPRFSNQAPNQQPTGRFDPQSPNQPPSAPRPQFPNQQPTGRFDPQFPSQPPRPQFPNQAPNQQSTGRFNPQFPNQRPSPPQSRFPDQAPNQQPSGPSPNRHPDRQGPPPRFQNQAPNQQPTGRFEPQPPNPPRAPPRPQTRLPNETSNEQPTAPGRSSGPASGYGIFSTPKTK

58.6 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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