IF-3 binds to the 28S ribosomal subunit and shifts the equilibrum between 55S ribosomes and their 39S and 28S subunits in favor of the free subunits, thus enhancing the availability of 28S subunits on which protein synthesis initiation begins.

Belongs to the IF-3 family.

273 amino acids

MAALFLKKLTLQTVKTENYCIRRCLGKYILQGPAPTQQPPRPSCLIHAKAFSTEDTQDEMTKKKKNETAFSSVGRKINERIIHVLDEQGNDLGHMHRANVIRLMAERDLRLVKRDASAEPPQYQLLTGAQIHQERLRLREAERAAPKPGPTLTKELTFSSNIGQHDLDTKSKQIQQWIEKKYKVQITVKKGKSADEPEDKMEEMCNRIVQTMSGIATFSSRPQPIRGGKAVMCVLRPLSKKEEAAWKAAPDTPRRDALNGGDGKDGASGVLPQ

30.6 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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