Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length.

Belongs to the GreA/GreB family. GreB subfamily.

160 amino acids

MKTKMITREGYNKLKQELDYLWKEHRPEITQKVSWAASLGDRSENADYTYNKRLLRQIDRRVRFLSKFLPEVKIVDYAPQQEGKVFFGAWVEIENEAGEVMKFRIVGPEEIYGDAKGYISIDSPMARALLKKEVDDEVQVPTPSGIKEWFINSIEYDKGE

18.7 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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