Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.

Belongs to the GreA/GreB family.

160 amino acids

MAEDKTYPMTEEGKVKLEKELEDLRINQRPEIINRIKIARSYGDLSENSEYESAKNEQSLLENRIKTVEHMLQYAEIIDSDKIDETEVSVGKIVTFKELPDEEPESYTIVGAAEADPMVGKISNDSPIAKGLIGHHVDEEVAINIPAGTMTVKILKVENA

17.9 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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