Transcription factor that regulates the expression of the gene clusters that mediate the biosynthesis of the host-selective toxins (HSTs) AK-toxins responsible for Japanese pear black spot disease by the Japanese pear pathotype (Probable). AK-toxins are esters of 9,10-epoxy 8-hydroxy 9-methyldecatrienoic acid (EDA) (PubMed:22846083). On cellular level, AK-toxins affect plasma membrane of susceptible cells and cause a sudden increase in loss of K(+) after a few minutes of toxin treatment (PubMed:22846083).

435 amino acids

MLQCAPKKNERLRGSCDFCTQSKLRCNKNKPSCRRCTIQQQVCVYSVARRTGRPPKHPRRADDSQETSGQHGHQDPMTSAPADSCEQQSSHLDLEGDDTDFTLVDGRTTAEGRATVAPPVLDNAFLMGETFEFNSLLDDPLVQSEDIFSFSPHIPRGEKGVHMASFHALNESTSPCSPSALLSIDVPQLPTNFRFLESFIGSELHGRNEPHPVEQPDEMEKTYDKGSILLGLDSAINAITNNGKDEPSISGWTVARPHSKHLCFCSMSMSKLQVLVSHPALCRQNSRTPFDMVLFLEEFVFGIHSDVLRCLICQSRSLHSLASLCICTDWVVEALVDVAQDLSLGQDNLGGLRAEICPPKNGSSIYVGRLILADQFRESCTRSLVKYRLRKLIPIMDTMIKLNYRGAGGALSQAIRTMVEDVRHKIESALGMMEL

48.2 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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