Together with tsp-14, regulates cell fate specification in the postembryonic mesodermal M lineage, body size and male development, probably by positively modulating BMP-like Sma/Mab signaling (PubMed:25978409, PubMed:28068334). May regulate BMP-like Sma/Mab signaling by mediating protease sup-17 trafficking to the cell surface (PubMed:28068334). Together with tsp-14, probably acts by modulating the activation of glp-1, a Notch-like receptor, to regulate germline maturation (PubMed:20220101). Probably acts by modulating the activation of lin-12, a Notch-like receptor, to regulate cell fate specification such as the anchor cell/ventral uterine precursor cell decision (PubMed:20220101).

Belongs to the tetraspanin (TM4SF) family.

308 amino acids

MANRRQPVQHRAQQRVYRQSQIRYAPGAGGESEISCCVKYSVFSFNVIFFLLGFGLLLFGVWAQIEKNTFVNMLSKASKLYLDPTWPLLIVGFLTFIIGFSGCVGSLRENTSFLTFYSTLLGLLLIAEFSAGVFAYACRDQLDNYIRNLLNDVVVGYRDDPDLQLLIDSMQETWMCCGINGADDWDRNTYFSIEAREVASPEAGGVPFSCCINSSKLEFKNYFCGHGVRLKPESHMAAHLAAQRVMAHTASIYTEGCLPKLQLWLNNNMLLVAVSMVIIAIIQVLGICFAQNLKSDILAQRAKWYYTH

34.7 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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