Probable transcriptional regulator involved in developmental processes. May act as a transcriptional repressor (Potential). Involved in two major neuronal regionalization processes: primary anteroposterior (AP) axis patterning of the CNS and segmentation of the cranial neuronal crest (CNS) development.

Belongs to the teashirt C2H2-type zinc-finger protein family.

1078 amino acids

MPRRKQQAPRRSAAYVPEEELKAADIEEDNLEDDGLSLDVQDSEYLYNDEHEIKETPSYQNSPISSATNQDAGYGSPFSETSDHLADFKSTSSKEGQDKEDGQNTENVSYPTDSLAQIKAVYTNLLSECCWSNLALDLKKSNENSSPTTNTNKSSMSEATGSTSDPDTPTTIPSSSCTNTSTSISVTTSNSTNSNSASGYDWHQAALAKTLQQTSYGLLPEPSLFSTVQLYRQSNKIYGSVFTGASRFKCKDCSAAYDTLVELTVHMNETGHYRDDNKDRDAERTKRWSKPRKRSLMEMEGKEDAQKVLKCMYCGHSFESLQDLSVHMIKTKHYQKVPLKEPVPAITKLIPSTKKRALQDIALPDSPEQAGISPGASVSESAKDPKAANPYVTPNNRYGYQNGASYTWQFEARKAQILKCMECGSSHDSLQQLTAHMMVTGHFLKVTNSASKKGKQLVMDAVIEEKIQSIPLPPTTHARLPGSYIKKQPDSPTGSTHSEEKKDPEKEKVNNCEVEKRIKEENEDPEKIEPATLYQYLREEDLDTSPKGGLDILKSLENTVSSAISKAQNGAPSWGGYPSIHAAYQLPGTVKALQPSVQSVQIQPSYAISVKTMTPDHNSLIHSPGSLTPPTHRSNVSAMEELVEKVTGKINIKKEEKVLEKEMVIPAKPPSPVAKENKEILKAEEANGKVLKKSNEADIQKPKKETPIEPHALNGTEPLKAKVTNGCSSLGIITDHSPEPSFINPLSALQSIMNTHLGKVSKPVSPSLDPLAMLYKISNSMLDKPIYPTTPVKQVESIERYYYEDSDQPIDLTKSKNKPFVTSITDHVSSPLRESALMDISDMVKNLTGRLTPKSSTPSTVSEKSDADGSSFEEAMDELSPVHKRKGRQSNWNPQHLLILQAQFASSLRETAEGKYIMSDLGPQERVNISKFTGLSMTTISHWLANVKYQLRRTGGTKFLKNLDTGHPVFFCNDCASQFRTASTYIGHLETHLGFSLKDLSKHSLNRIQEQQNVTKVITNKALSSVGGLIEEDSSSTFQCKLCNRTFASKHAVKLHLSKTHGKSPEDHVIYVTELRKQ

119.2 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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