Description
Functions redundantly with TRAF1A in the regulation of plant immune response. Contributes to the turnover of the nucleotide-binding domain and leucine-rich repeat-containing (NB-LRR) immune receptors SNC1 and RPS2. May associate with an E3 ubiquitin-protein ligase complex, which modulates ubiquitination and subsequent degradation of NB-LRR immune sensors to maintain their homeostasis (PubMed:26867179). Functions redundantly with TRAF1A in the regulation of autophagosome formation. Required for SINAT1- and SINAT2-mediated ubiquitination and destabilization of ATG6. Functions as molecular adapter that helps to regulate autophagy by modulating ATG6 stability (PubMed:28351989).
Species
Arabidopsis thaliana
Sequence
MAEAVDEDSGVGRSLEESSNGQHSQAGEALSEWRSSGQVENGTPSTSPSYWDIDDDDDYGLKPSELYGQYTWKIPKFSEITKREHRSNVFEAGGYKWYILIYPQGCDVCNHLSLFLCVANYDKLLPGSFAILEAGWSQFAQFTISVLSQDLKKSKFSDTLHRFWKKEHDWGWKKFMELPKLKDGFIDESGCLTIEAKVQVIRERVDRPFRCLDCGYRRELVRVYFQNVEQICRRFVEEKRSKLGRLIEDKARWTSFGVFWLGMDQNSRRRMCREKVDVILKGVVKHFFVEKEVSSTLVMDSLYSGLKALEGQTKNMKARSRLLDAKQLPAPIVSVDKDMFVLVDDVLLLLERAALEPLPPKDEKGRQNRTKDGNDGEEVNKEADERDERRLTELGRRTVEIFILSHIFSTKIEVAHQEAIALKRQEELIREEEEAWLAETEQRAKRGAAEREKKSKKKQAKQKRNKNKGKDKRKEEKVSFATHAKDLEENQNQNQNDEEEKDSVTEKAQSSAEKPDTLGDVSDISDSVDGSADILQPDLEDRDSSSVLWDTDALEIHPPSSEGSSRGRGISISTPNGITEGKSHSTMDDSSSTCSNDSIRSGVTNGSYQGNSLNFRNQKSPNKGKNQQVKAMTDAHSLASETDDQPSTLGTDPKGQNYSSEASNVGESDWVVVSHIQEPEGSRNRIPVGRERKTVQSIVNSVDMDRPKEKSTAVLSSPRNVAKNPSPLTQTKPEKKSISTADGIPNRKVLATGPPSSSQVVLPSDIQSQTVGLRADMQKLSAPKQPPATTISRPSSAPIIPAMRPSPITVSSSVQTTTSLPRSVSSAGRLGPDPSLHNQQTYTPQSYKNAIVGNSLGSSSSSFNHHPSSHGVVPTTLPSSSYSQAPTSSYQSSFPYSQDGLLWTGRSPSSVNMGMYNNTYSPAVTSNRSLNHMDVQIAQQQAQSMMTDEFPHLDIINDLLEDEQCSNMVYNGSIFNPQPQVFNGQYSSYHGELLSGGRTRSFGEEGLHYMARGPYGTDGMMPRQWQMTNMDLSLPAMRSNGMEDGTSSAANYHHSYFGLDASNPSFTSGINGYTEFRPSNGH
Simulated SDS-PAGE

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
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Protein synthesis service