May act as a GTPase-activating protein for Rab family protein(s). Signal effector acting as a linker between RAC1 and RAB7A, leading to RAB7A inactivation and further inhibition of cadherin degradation (By similarity).

925 amino acids

MEGAQESPAESGSSVPWSEEPAGSAKVPEVSLSEESEGCTRPLEATPPKLCGYLSKFGGKGPIRGWKSRWFFFDERKCHLYYSRTAQDANPLDSIDLSSAVFDCKADAEEGTFEIKTPNRIITLKAATKQAMLYWLQQLQMKRWEFHNSLPALPAAHDAALAGNGPALRLELEQEEEEEEAFLCPVKTPTDLVGVAAAWQPVHARPLALQNISLKHLGTEIQNTMCNIRGNKQTQGANHRPPGEDSPLIEETQREEQPSPPGPGAPGKDPANSLKSSLTTSLIRKAKSQSNTFPLFSEGLMRNRTAQEKVLALEQQVLMLTKELKAQKELVKILHKALEAAQQEKRVSSAYLAAAQDKDRLELVRHKVRQIAELGRRVEALERERESLAQTASLQEQEIRELQQHVQLLLDKNQAKQQVICKLSEKVTQDFMKAPEEADRDFLSQQEKMEHLKDDMEAYRTQNRFLNSEIHQVTKIWRKVAEKEKALLMKCAYLQAQNCQVESKYLAGLRRLQEALGVEAGECSELLRQLIQEALQWEASEASADSVVLSPSTISEYDEYGFLTVPNYEVEDLRLLAKIQALEVHSHHLLAHEAVERPLRERWATLGELAPSAELKQLLRAGVPHEHRPRVWRWLIRLRVQHLQAPGCYQALLSRGQACKHSAARQIELDLNRTFPNNKHFTCPTSSFPDKLRRVLLAFSWQNPTIGYCQGLNRLAAIALLVLDEEESAFWCLVAIVETIMPADYYSKTLLASQVDQRVLQDLLLEKLPRLMAHLGQRHVDLSFITFNWFLVVFADSLISNILLQVWDAFLYEGIKVVFRYALAIFKYNEEALLRLQDSLEIYQYLHFFTKTICDSRKLMHIAFNDMNPFPMKQLRQLRAAHRERLEAELNELEQLKAEYLETRAAQGPAVPEGSPSEDEGEAEP

105 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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