Plays a role in planar mitotic spindle orientation in retinal progenitor cells (RPCs) and promotes the production of symmetric terminal divisions (PubMed:26766442). Negatively regulates the mitotic apical cortex localization of GPSM2 (By similarity). Involved also in positive regulation of cell proliferation and tumor cell growth (By similarity).

391 amino acids

MAVAAMAERGRLSHAAPAPSTEGLPRAFLQSLRTLFDILDDRQRGYVHLREIESRWQGADARELPCGVLEGLRQVAPANGYLTFERFVAGLRTSLLKADGGQRDQARVAARPGDQSSLQQRLMFAPADEPRTVLERKPLPLSACPASGGPSGTSRNPELLCVPVEAASCPTETERPLSKALEQIPSADLGAAACKTLGKGTGEARQAPRARGERRRHTITNGVDCSLLKQMKELDQEQEVLLQGLEMMARGRDWYQQQLQRVQERQRRLSQSRAAADFGAEGSPRPLGRLLPKVQEVARCLGELLTAACSGRALPSSSLGPLGPPSPSTPVWQQQTILMLKEQNRLLTQEVTDKSERITQLEQEKSALIKQLFEARALSQQDSGPLDSTFI

42.8 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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