Central component of cohesin, a complex required for chromosome cohesion during the cell cycle. The cohesin complex may form a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. Cohesion is coupled to DNA replication and is involved in DNA repair. The cohesin complex plays also an important role in spindle pole assembly during mitosis and in chromosomes movement (By similarity).

Belongs to the SMC family. SMC3 subfamily.

1193 amino acids

MYIKQIRLKGFRTYKNETTIDFTRGINCIVGFNGSGKSNILLAIEFILSDVCEYKQIYLHEGIGNAVRNCYVEIIFDNSEKYFSMFKESEIKIKKVLENMKCEIFVNDKNISKNQYVELLESCGLCINNLYNIIKQGQIIKLSNMKDEEILNYLKSILGAKIFEEKKKDALSMLKECDSKKVTIEKEFNDMNSKLESLQEEFENFLEYKKLEKEKVHLDYFLNEINYKNIYEETQMLKSKLQELKNKTQDEDNHLNLSNNNKSEYNEKLNKMKLEIASCQNHLNKTISEDIQNKRNIVHLQMLIDEKIKEKNIKESQNKNRIKNINQINEFILRVNEKLQSLKSDIVSKEKQIENKNNEINMLLSKNKNKNTDANYSHNVKKIEKMINDINIELSFLEKETIKNEKYLKELEEESKVLNKSIKENETLSQKYGSEINELNNKSEKCVEQKRQCQQKISEGTTNLNEIKCQIIEVNDKYDEIIKSSNKEILKIVDLIMAEKSIKRENILGFLIDNINVDKTYVKAVDTILENHYFTLIVEDMQTAKKIVEFIEKKREERTSKEFNFKEFYFGKLTIVPLLNIKKFNEFNYPNDKNIVPLIKCVNYNSKIYEFLKNILFKTIIVKSLESCENYLEDNYNCVNIDGDYLSKHGFMYGGYNKKKYGIYTVYNKLKELKEEEKKEKSHIEELNNNIEKIDDELRNIYDTKSSTVAKKNGCASTINSINNNIYSNEENIRLTSEKINYIQEKKQNLEQHKDQLKMQILQLRNNNVNPDESEKVGSTDINSLNDEVKKLKEELNKIRNEYDDFKNKLELLYQKRNENDSSIYMEEYEDVDIDEYNNDLADKKDHSDKIEKEKIHYEQKIREINKEMENVKSSIDKILINEKKHKKKILDLCHQMNQINEELRILEGKEENIRKKKVLLPQGIQELEEYRTYDKQQLSAKLKSVTMELKKYSNVNEKAGDRLNILMNDFNELKKRHEEINSSHKNIKDMIQHIGKKKDEALEATYVKINKYFSEYFSLLFKNRKASLVLKKMNEKEYKEKLQEMSEKRIKRRIIDEEVYIDKITGISINITSNDDEKMTYTIQELSGGERSIVAICLFLCLNKIDNFSFFFFDEIDAALDTIHRDNLSLLLKELAHRGTQFIITTFRKELLEYSDNMYIVKIVDRESYISKGTKNEAYEIISIEEKHALEN

141.2 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.

Make PFD0685c using our protein expression services starting at $99 + $.30/amino acid in as fast as two weeks (includes the cost of DNA synthesis)

Order Here