Protein expression services for SPEF2 | Sperm flagellar protein 2
Description
Required for correct axoneme development in spermatozoa (PubMed:16549801, PubMed:19889948). Important for normal development of the manchette and sperm head morphology. Essential for male fertility. Plays a role in localization of the intraflagellar transport protein IFT20 to the manchette, suggesting function as an adapter for dynein-mediated protein transport during spermatogenesis. Also plays a role in bone growth where it seems to be required for normal osteoblast differentiation (By similarity).
Species
Sus scrofa
Length
1812 amino acids
Sequence
MSEILCHWLNQELKVSQTVSPKSFAKAFSSGYLIGEVLHKYELQDDFAEFSEKRISSAKLNNFSRLEPTLHLLGVQFDQNVAHDIITEKPGVAMKLLYQLYIALQRKKKSGLTGVELQTMQPLTNTKLQNMKSEAFRDRLRNLIPRQTDVSLMRVSHRFQEKYKYKDEDLVHTHLKKLENFQKLQEEQRSFNIEKQRLSRRRQNEIMAQIQAAIIQIPKPASNRTLKALDAQKMMKKKKEAEDVANEIKKFEALIKKDLQAKESASKTSLDAAGQTTTDLLNTYSDDEYIKKIQKRLEEDAFAREQREKRRRRLLMDQLIAHEAQEEAYREEQLVSRLMRQSQQERRIAVQLMHVRHEKEVLWQNRIFREKQYEERRLKDFQDALDREAALAKQAKIDYEEQALREKEMHEQIAAERVQARYKKHYSICAEILDQILDLSTKVADYRMLTNNLIPYKLMHDWKELFFNGMPIYEQASLKHLSAKPSTEQLIELEKRDLLDNNDYEEYKNMVGEWALPEEMVDNIPPSDNRILGHVIHRLIEHSLPPQVESTAPELPSFAIKGCLLGKTFSGKTTALKFLQKYFPIEVLSIDTLVQEAIQAFHNNEKVSGALQLQKAAEEKASPVRQESGDRSQNLHNVLSAEGTPETEDETRLSTKKTPKAEEVIASASLSELTTRAQLGAKSEKLLKKGKSISDTLLVSIVVNAINQIPIYKGWILDGFPMTLNQAKLLEEALTGFNRNLIELEGKKSQISTLAVDPTASREVPLPPSAFDFVMLLDISDNTSLNRMNDIMAEAFLSETPHENINQRVAAENQDMDEDQNLRDQIQHRIIGFWDHWPSLEQWFTEPENILIKMNAEVDEQSLCQKVKEMFMAEIMKKENKAKKKSEEKEAEKKEEFSLPEATPPTPPAPPPSEPEKEKEAHPPHERSKTPTAKGKPASEPPHGNRESPQEGKGKKSETSPKRKGSPRGKSPGGKAPVKKSPADSTDVSPVPAVPPPSKPGSEEWVFVNEPIPEEIPLFLVPYWKLIENSYINSIKTVLRHLREGQHTVLAYLYDTRTGFQQFLRRPDHKQNFVSQWQADFNSLPDDLWEDEETKAELHQRVNDLRDRLWDICDARKEEAEQERLDIINESWLQDSTGIAMNHFFSLMQAELNRFQDTKRLLQDYYRGMECKIPTDDTKRFTRIPLVQLDNKDTLEFQLRIPLVPRRSISPESALSKPKIKALLKGNIDYSLENVELNFEADEKVVMDTWQQASLAVSHMVAAEIHQRLMEEEKENQPADTKEKPPQAAANKKVKKEPPKKKREDKKGKGKSPPMAESAPVITVEEIAEMERKNELRLRIKEEHLAALQFEERATQFRLELIKTKALAFLEDLVTKAVDVYKLMEKWLGERYLNEMASVEKLTEVARYHIETSTKIQNELYLDQEDFFINGNIKVFPDPPPPVRPPPVEKEENGTLTIEQLDNLRDQFLDIAPKGVIGNKAFADILLDLVTLNLGTNNFPSSWMHLTQPELQELASLLVINSELVDWRKFLLVAALPWPIPLEEELLETLQRFKAVDEEQLGTVTFEQYLQAGLWFTGDKDIKIPANPLEPLPFNRQEHLIEFFFRLFADHDKDPPRLDYTEMLLYFACHPDGMEGVYRALSVATGSHVFQPIETPVLVAEKTSSFIDMSPTEEYPEPEDNFISEERELQEEGEEKEEDIPENANTEMISMETLLKVFRGGNEPQDTNRFASYPKTESIYSENFIKVFQDLGSKNLEPIEVAVLLKHPFIQDLIRSYPDYKIPDIKVVLQRSEHIQGSDGESSPSRLTEEKK
Mass
208.8 kDa
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)Safety
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Protein synthesis service
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