Protein expression services for spas | Spastin
Description
ATP-dependent microtubule severing protein. Stimulates microtubule minus-end depolymerization and poleward microtubule flux in the mitotic spindle. Regulates microtubule stability in the neuromuscular junction synapse. Involved in lipid metabolism by regulating the size and distribution of lipid droplets. Involved in axon regeneration by regulating microtubule severing.
Family
Belongs to the AAA ATPase family. Spastin subfamily.
Species
Drosophila willistoni
Length
777 amino acids
Sequence
MVRTKSSSSSASSSSQKSPIKSNNGAGGGGSSSSHRQSHRTSIDERKSSSHAHSNNSNVSSSSRRAATATSGSSSPEGDDDTTTDDLTPTGSSPRSCNGRGHSSVHKQNLYVVSFPIIFLFNVLRSLIYQLFCIFRYLYGASTKVLYRPHRRDCNIEIVVQNSKEQQLQLQQHQHNQTLSYSLETGGVSGGSGGEQQVQVQPQRIRALQPLEMATNRPGGGYSPGPGDPLLAKQKHHHRRAFEYISKALKIDEENEGHKELAIELYRKGIKELEDGIAVDCWNGRGDVWDRAQRLHDKMQTNLSMARDRLHFLALREEDLQMQRLSLKEKQPAPKQPQRSQTKDPVKQPMLTSLNADPVKMKVRSSGYGPKQNGTSSSRPAPSGQTATGASGRKLTVGTKRPGNLPVTNKSQTLPRNLGSKTTVGAVQRQPAKTAATPPAVRRQFSSGRNTPPQRSRTPINNNASSGSGASTPMVSVKGVEQKLVQLILDEIVEGGAKVEWTDIAGQDVAKQALQEMVILPSVRPELFTGLRAPAKGLLLFGPPGNGKTLLARAVATECSATFLNISAASLTSKYVGDGEKLVRALFAVARHMQPSIIFIDEVDSLLSERSSNEHEASRRLKTEFLVEFDGLPGNPDGDRIVVLAATNRPQELDEAALRRFTKRVYVSLPDEQTRELLLNRLLQKQGSPLDTEALRRLAKITEGYSGSDLTALAKDAALEPIRELNVEQVKCLDISAMRPITEKDFHNSLKRIRRSVAPQSLNSYEKWSQDYGDITI
Mass
85.1 kDa
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)Safety
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Protein synthesis service
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