Description
ATP-dependent microtubule severing protein. Microtubule severing may promote reorganization of cellular microtubule arrays and the release of microtubules from the microtubule organizing center following nucleation.
Family
Belongs to the AAA ATPase family. Spastin subfamily.
Sequence
MASTVALLRDSSDDRENFDDGETDCVQVGRKRKLTVFFYPLLLVFWLLRWVFYQFFLVLCFVCRGFVPRRHLATAETTTTMATAEEPDANLLIRQKQHHKKAFDFISKALKYDEENEDFKEMSIDLYRKGIEELQKGIAIDFSKGQGTTWERAHRLSDKMKVNLEMARDRLDFLESMVKIEHLGDHLPWHGGVAPAQRGQRRRAWQKAAPSAPSEPGTGPSWLKMAENGPAKGGPCPTSPRLQRSNTGVTLRRQQQQQLGGVSTVSRSQTLPRNSVPCPRMSARSPSRKAGNNEAVPTPNTARRRASQPQVPPVHPRGRQPTTRGGAAHRGGPPTVSQRSLLSSRVPPLKGVDSRLAHLILDEVVDGAPPVLFSDIAGQEVAKQALSEMVILPTDRPELFTGLRAPPKGLLLFGPPGNGKTMLAKAVAHESNSTFLNISAASLTSKYVGEGEKLVRALFAVARELQPSIIFIDEVDSLLSERKDNEHEATRRLKTEFLVEFDGLHTGSEERVLVMGATNRPQELDDAALRRFTKRVYVTLPDHNTRVILLEKLLKKHNNPLSADKLKYLARLTEGYSGSDLTALAKDAALGPIRELNPEQVRCVDPKKMRNISLQDFLDSLKKVRRSVTPQSLDFFDRWNREFGDITV
Simulated SDS-PAGE

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service