Functions in the transition of mRNAs from translation to an mRNP complex destined for decapping. High-copy-number suppressor of decapping defects. Overexpression suppresses decapping defects in both DCP1-2 and DCP2-7 mutations. Acts to promote translational repression of mRNA in conjunction with DHH1 and subsequent mRNA localization to P bodies. Promotes translational repression of mRNA during glucose deprivation.

Belongs to the RRM GAR family.

294 amino acids

MSAEIEEATNAVNNLSINDSEQQPRAPTHKTVIDPEDTIFIGNVAHECTEDDLKQLFVEEFGDEVSVEIPIKEHTDGHIPASKHALVKFPTKIDFDNIKENYDTKVVKDREIHIKRARTPGQMQRGGFRGRGGFRGRGGFRGGFRGGYRGGFRGRGNFRGRGGARGGFNGQKREKIPLDQMERSKDTLYINNVPFKATKEEVAEFFGTDADSISLPMRKMRDQHTGRIFTSDSANRGMAFVTFSGENVDIEAKAEEFKGKVFGDRELTVDVAVIRPENDEEEIEQETGSEEKQE

33 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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