Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins.

Belongs to the TMEM97/sigma-2 receptor family.

176 amino acids

MGVPATRRCVEWLLGIYFLSHIPITLFMDLQAVLPRELYPVEFRNLLKWYAKEFKDPLLQEPPAWFKSFLFCELVFQLPFFPIATYAFLKGSCKWIRTPAIIYSVHTMTTLIPILSTFLFEDFSKASGFKGQRPETLHERLTLISVYAPYLLIPFILLIFMLRSPYYKYEEKRKKK

20.9 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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