Involved in the control of sexual development and cell growth under stressed conditions. Phosphorylates AGC kinase gad8 at 'Thr-387', activating gad8 kinase activity and promoting sexual development (PubMed:12805221). Phosphorylates AGC kinase psk1 at 'Ser-248', activating psk1 kinase activity and promoting phosphorylation of ribosomal protein S6 (PubMed:22976295).

Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PDPK1 subfamily.

592 amino acids

MRNTHNPNETEASEDAENDTQSESDLSFDHGSSEKLNRASLPKTQNSAIPQSNALNTTPNESTSQIDSSPKIPSAVPHISTPNPSSGASTPNIKRVSDFKFGEILGEGSYSTVLTATENSTKREYAIKVLDKRHIIKEKKEKYVNIEKEALCILSKHPGFIKLFYTFQDAHNLYFVLSLARNGELLDYINKLGRFNEICAQYYAALIVDSIDYMHGRGVIHRDLKPENILLDDNMRTKITDFGSAKILNSSHGSHEEDTHHADKPQAHSRSFVGTARYVSPEVLSDKIAGTASDIWAFGCILFQMLAGKPPFVAGNEYLTFQSILHLSYEIPPDISDVASDLIKKLLVLDPKDRLTVDEIHQHPFFNGIKFDNTLWELPPPRLKPFGHTSVLSLSVPNASNKHENGDLTSPLGVPSMVSASTNAAPSPVGTFNRGTLLPCQSNLEEENKEWSSILQDDEKISKIGTLNVYSMSGINGNDAFRFFSSLFRKRKPRTFILTNFGRYLCVASDGEGRKTVKEEIPIKSVGMRCRMVKNNEHGWVVETPTKSWSFEDPNGPASAWVELLDKASSISLPFGNHSVTSFSRSIARSAV

65.7 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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