Description
Has a role in the Wnt signaling pathway controlling the asymmetry of cell divisions during embryogenesis. Operates in the AB and EMS cell lineages influencing cell specification. Required for body wall muscle development, endoderm development, pop-1 asymmetry and T-cell division asymmetry. Lit-1/wrm-1 complex regulates pop-1 localization and is required for pop-1/par-5 interaction (By similarity).
Family
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Species
Caenorhabditis briggsae
Sequence
MPSSTLLELAPNTHSKCKFETRNRSSSSSSGCSSSSTELYDLAAAHAALISRQQQILNQGIPIIPEHQLAAAAVAHHHHQLHPSVQHQLVAGHHHHHLPQVAHHPAILPRSDVIQQPSHFALHQHLQNLVQQQQQQQALHHHQQLVGDMALVSHTHPAAVGSTTCYEKNPQKQQQVPQIPTQPQVAHVSSNAILAAAQPFYQPPVQDSQPDRPIGYGAFGVVWSVTDPRSGKRVALKKMPNVFQNLASCKRVFREIKMLSSFRHDNVLSLLDILQPANPSFFQEFTSWHLTPSIHHQRLISHIKPICLFFVLPLVSLLCAHMYVCMWWHGTALLEGRKETITYVLTELMQSDLHKIIVSPQTLTIDHVKVFVYQILRGLKYLHTANILHRDIKPGNLLVNSNCILKICDFGLARTWDSRDRLNMTHEVVTQYYRAPELLMGARRYTGAVDIWSVGCIFAELLQRKILFQAAGPIEQLQMIIDLLGTPSQEAMKYACEGAKNHVLRAGPRAPNLQSLYRLSQQTTDDAVDLLVKLLKFNPDERISVEEALSHPYLEEGRLRFHSCMCSCCYTKANVPSRIFSQELDPKHESPFDPKWEKDMSRLSMFELREKMYQFVMDRPALYGVALCINPQSAAYKNFASSSVAQASELPPSPQAW
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service