Member of the two-component regulatory system SpaK/SpaR involved in the regulation of the biosynthesis of lantibiotic subtilin. SpaK may function as a membrane-associated protein kinase that phosphorylates SpaR in response to environmental signals.

459 amino acids

MGIGFKGRKTLLRELVKYMVTLCISLVVLALLYIFINTIAMNTGFSHPANYNEREAEKLAPKLETIDKVTADMIPDTMSYAILNKETKQKTAGTIKEKDLQLVKKKIEKKPYVNYKQKGYLVIERNNEYCVLQYSLRADFSSPLLRKYLPNYELTSICILIILLIIVISIITTYFANRLRKHFETLNVITRYIKEQNLQFTPEFTHIKEFDDVIDSLIEMRDALQSSLEALWRLEKNKKEQIGALAHEIKIPITIIKGNAELLSLSMQNEEQAEYTKYILGAGNQIEQYIYQLIHLSKTEDALTIHLEKASVDELTETLVKDISAYKGNKNINISFKKENLMKEAKIDWQLLHRALLNILTNAVDYTPEGGTVSVHAECDSEIFYFFVKDTGNGFSEMGLKKATELFYMDDKSRHSKGHYGMGLTFAKNAVNLHNGELTLGNTIAGGAEVRVKIPLRNE

52.5 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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