May be a stop signal for the dorsal root ganglion neurons in their target areas, and possibly also for other neurons. May also be involved in the maintenance and remodeling of neuronal connections (By similarity).

Belongs to the semaphorin family.

931 amino acids

MPRAPHSMPLLLLLLLLSSLPQAQAAFPQDPTPLLTSDLQGASPSSWFRGLEDDAVAAELGLDFQRFLTLNRTLLVAARDHVFSFDLQAQEEGEGLVPNKFLTWRSQDMENCAVRGKLTDECYNYIRVLVPWNSQTLLACGTNSFSPMCRSYGITSLQQEGEELSGQARCPFDATQSTVAIFAEGSLYSATAADFQASDAVVYRSLGPQPPLRSAKYDSKWLREPHFVYALEHGEHVYFFFREVSVEDARLGRVQFSRVARVCKRDMGGSPRALDRHWTSFLKLRLNCSVPGDSTFYFDVLQSLTGPVNLHGRSALFGVFTTQTNSIPGSAVCAFYLDDIERGFEGKFKEQRSLDGAWTPVSEDKVPSPRPGSCAGVGAAASFSSSQDLPDDVLLFIKAHPLLDPAVPPATHQPLLTLTSRALLTQVAVDGMAGPHRNTTVLFLGSNDGTVLKVLPPGGQSLGSEPIVLEEIDAYSHARCSGKRSPRAARRIIGLELDTEGHRLFVAFPGCIVYLSLSRCARHGACQRSCLASLDPYCGWHRSRGCMSIRGPGGTDVDLTGNQESTEHGDCQDGATGSQSGPGDSAYGVRRDLSPASASRSIPIPLLLACVAAAFALGASVSGLLVSCACRRANRRRSKDIETPGLPRPLSLRSLARLHGGGPEPPPPPKDGDAAQTPQLYTTFLPPPDGGSPPELACLPTPETTPELPVKHLRASGGPWEWNQNGNNASEGPGRPPRGCSGAGGPAPRVLVRPPPPGCPGQAVEVTTLEELLRYLHGPQPPRKGSEPLASAPFTSRPPASEPGASLFVDSSPMPRDGVPPLRLDVPPEGKRAAPSGRPALSAPAPRLGVGGSRRLPFPTHRAPPGLLTRVPSGGPARYSGGPGRHLLYLGRPEGHRGRSLKRVDVKSPLSPKPPLASPPQPAPHGGHFNF

99.5 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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