Binds to plexin family members and plays an important role in the regulation of developmental processes. Required for normal cardiovascular development during embryogenesis. Functions as attractant for growing axons, and thereby plays an important role in axon growth and axon guidance (By similarity).

Belongs to the semaphorin family.

751 amino acids

MAFQAVCILVGVFVCSTYVKGSPQPQARVYLTFDELRETKTSEYFSLSQYPLDYRILLMDEDQDRMYVGSKDHILSLNINNISQEPLSVFWPASAIKVEECKMAGKDPTHGCGNFVRVIQAFNRTHLYVCGSGAFSPVCAYLNRGRRSEDQVFMIDSKCESGKGRCSFNPNVNTVSVMINEELFSGMYIDFMGTDAAIFRSLTKRNAVRTDQHNSKWLSEPMFVDAHVIPDGTDPNDAKVYFFFKEKLTDNSRSTKQIHSMIARICPNDTGGLRSLVNKWTTFLKARLVCSVTDEDGPETHFDELEDVFLLEMDNPRTTLVYGIFTTSSSVFKGSAVCVYHFSDIQTVFNGPFAHKEGPNHQLISYQGRIPYPRPGTCPGGAFTPNMRTTKEFPDDVVTFIRNHPLMYNSIYPVHRRPLIVRIGTDYKYTKIAVDRVNAADGTYNVLFLGTDRGTVQKVVVLPTNSSARSELILEELEVFKNHAPITTMKISSKKQQLYVSSNEGLAQVSLHRCHIYGSACADCCLARDPYCAWDGHSCSRFYPTGKRRSRRQDVRHGNPLTQCRGFNLKAYRNAAEIVQYGVKNNTTFLECAPKSPQASIKWLLQKDKDRRKEVKLNERIIATSQGLLIRSVQDSDQGLYHCIATENSFKQTIAKINFKVLDSEMVAVVTDKWSPWTWASSVRALPFHPKDIMGAFSHSEMQMINQYCKDTRQQHQQGEESQKMRGDYGKLKALINSRKSRNRRNQLPES

85.2 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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