Description
Regulates the formation or stabilization of cell-cell contacts at several stages of epithelial morphogenesis. In early embryonic development, required for proper ventral closure of the epidermis. During male tail morphogenesis, regulates precursor cell sorting and allows the formation of distinct sensory rays. Seems to control cell-cell contact formation through 2 parallel pathways, one involving efn-4 and one involving plx-2 and unc-129. May also be involved in axon guidance.
Family
Belongs to the semaphorin family.
Species
Caenorhabditis elegans
Sequence
MRNFLVFSVIFIAYNSCEAANIQADNTFADPNIGEFRELLIDPKAGALFVGSEGAIFRLWAYNINDTGENVFAKKQLVLSESEESECRSTASDERLCRPSTRFLAFTNNLDSIYVCSSVGMRPEIRVLDSLSLRDQQEPRTEIGICVVDPTFNFTAVVVDSGNPEDATSVYSGIRTGMGGENHLIYRPPLTKNGKQLHASIRTIYSDNKWLNEPQFVGSFDVGQHVFFFFREIAHDNSFGERIVHSRVARVCKKDIGGRNVLRQVWTSFVKARLNCSVSANFPFYFDHIQSVKRVDKHGETYFYATFSTSETAFTSSAICMFQLSSINHLLDTGLLMEETANGQFSVTADEIPAHRPGTCSQNSHSISDTDLHFAKTHLLVSDSISGGTPILPLRDHVFTHIVVDQLPNQNVIFAFDSANRRVWKISHWKEGNEWKSNLIEEKSLKIAASRINDVALLPAEFFFVTSGAGVSQFSVARCSEQPSCALCSLDPYCSWNAVNSKCSLKTKTNEKSVGWISSSWAGRISPECSAVEKLTVKDVYLGDGLRLVGAKNGVWQKDGRSVESGQRHVVTRNGELVVLDAQLEDAGTYECLRDNIILVRARIVVHENCARPTSVAEYRSCQREWCKKADAYKAALNIWSDSNKKNVQCKANTSSAH
Simulated SDS-PAGE
(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)
Safety
Upon ordering, we will perform rigorous biosecurity and export control screening to ensure that order fulfillment is consistent with all legal and regulatory guidance.
Protein synthesis service