Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. SelB subfamily.

634 amino acids

MPVIMGTAGHIDHGKTSLIKALTGINCDRLAEEQKRGITIELGFAYLDLTPEVRLGIIDVPGHERFVKNMVSGAAGIDFVLLVIAADEGIMPQTREHLEICSLLGIRAGLVALTKTDMVEEDWLELVHEEVQTYLAGSFLEGAPIVPVSAHTGAGLEELKGYIAELSSTFAPDRRSDLFRLPVDRVFTMKGHGTVVTGTSISGALRLGEEIEIVPSGHRSKVRGLQVHGTAAEVARAGERTAVNLYGLEVAELERGEVLAHPQTLFPSPVWDVEMTCLSSSPNPLKHRTEVHFHHGSREILAKLFFLDRDKLEPGETAVCQVRFPRPLPGVYGDRCIVRSFSPLQTVAGGRIINPLGRKVRRHSKDMETLSTLGAATGEELLLAQLRLAGRGGLTVAELRIMTDMESKLLDKTLQILGGKQLAFQFDRDDKRFVGADVLDGLAGACLEYLGEYHRREPMRQGLSRAELISGFGRGMHPKLVHFLVERLVKSGQVLLEADILRLPGHVVSLASDQSGLRTLMETTYVQAGLMPPTTKAFLEENGLTAKDVAQMFRLLMEEGVLIKVSEEFYYAKTAMDEIIGRVRSFFESNQEMGPQDFRDLTELTRKFAIPVLEYLDKEKITMRIGDKRQIRKR

70.1 kDa

(Note: Representative image - actual molecular weight may vary depending on tag type and expression method)

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